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- W2157022205 abstract "A rapid and simple electrochemical detection method has been developed to detect the presence of protease (HIV-1 PR) in HIV patients' sera. In this assay format, disposable screen printed gold electrode (SPGE) surface was modified with gold nanoparticles (AuNPs) or thiolated single-walled carbon nanotubes/gold nanoparticles (SWCNT/AuNPs). Thiol-terminated ferrocene (Fc)-pepstatin was then self-assembled on such modified surfaces. The interaction between the Fc-pepstatin modified substrates and HIV-1 PR was confirmed by scanning electron (SEM) and atomic force microscopy (AFM) and probed by differential pulse voltammetry (DPV). A linear relationship was observed between the shift in peak potential and the increasing number of HIV-1 viral replications in the HIV-infected serum samples." @default.
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- W2157022205 date "2010-07-06" @default.
- W2157022205 modified "2023-09-26" @default.
- W2157022205 title "A Sensitive Electrochemical Assay for Early Detection of HIV-1 Protease Using Ferrocene-Peptide Conjugate/Au Nanoparticle/Single Walled Carbon Nanotube Modified Electrode" @default.
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- W2157022205 doi "https://doi.org/10.1080/00032711003653924" @default.
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