Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157049787> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2157049787 endingPage "48" @default.
- W2157049787 startingPage "44" @default.
- W2157049787 abstract "Vascular complications after renal transplantation causing initially only partial renal ischemia can be difficult to discover in time to save the kidney. Our aims were to design an animal model allowing progressive and stepwise reduction of the arterial renal blood flow (RBF) and to investigate whether microdialysis could detect the subsequent metabolic changes.Eight pigs were used. Two microdialysis catheters were placed, one in the lateral renal cortex, the other just outside the renal capsule. Baseline measurements were obtained at steady state. Five injections of 100 mu-polyvinyl alcohol (PVA) particles were administered once every hour through an angiographic catheter placed in the renal artery to cause the RBF to gradually decline. The glomerular filtration rate (GFR) was estimated by (51)Cr-EDTA.One diseased animal was excluded. GFR, RBF, and all metabolites measured by microdialysis remained stable during 2 hours of baseline measurements (ANOVA; P > .05). Within 30 minutes, the first injection of PVA particles caused a reduction of RBF to 40 +/- 13% of the baseline flow (t test; P < .001 vs baseline). Significant changes in cortical lactate and glutamate as well as extracapsular glutamate were also seen, at indicating ischemia (n = 7). Cortical glucose changed 60 minutes after baseline (n = 7).Acute, stepwise renal blood flow reduction was achieved by injection of PVA particles. An early warning of developing ischemia is provided by microdialysis. This technique could be clinically valuable because it could be instrumental in improving survival of transplanted kidneys suffering from postoperative ischemia." @default.
- W2157049787 created "2016-06-24" @default.
- W2157049787 creator A5000546523 @default.
- W2157049787 creator A5008324975 @default.
- W2157049787 creator A5010600188 @default.
- W2157049787 creator A5049619456 @default.
- W2157049787 date "2009-01-01" @default.
- W2157049787 modified "2023-10-13" @default.
- W2157049787 title "Detection of Local Metabolic Changes After Progressive and Stepwise Reduction of Renal Blood Flow in Pigs" @default.
- W2157049787 cites W1970248671 @default.
- W2157049787 cites W1977545059 @default.
- W2157049787 cites W1995576941 @default.
- W2157049787 cites W2003826266 @default.
- W2157049787 cites W2034460888 @default.
- W2157049787 cites W2042230896 @default.
- W2157049787 cites W2063084903 @default.
- W2157049787 cites W2070068969 @default.
- W2157049787 cites W2089139897 @default.
- W2157049787 cites W2094399768 @default.
- W2157049787 cites W2131953296 @default.
- W2157049787 cites W2144364488 @default.
- W2157049787 cites W2164035349 @default.
- W2157049787 cites W2187766168 @default.
- W2157049787 cites W2207311322 @default.
- W2157049787 cites W2313100408 @default.
- W2157049787 cites W2334113789 @default.
- W2157049787 cites W2416203963 @default.
- W2157049787 doi "https://doi.org/10.1016/j.transproceed.2008.10.089" @default.
- W2157049787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19249471" @default.
- W2157049787 hasPublicationYear "2009" @default.
- W2157049787 type Work @default.
- W2157049787 sameAs 2157049787 @default.
- W2157049787 citedByCount "10" @default.
- W2157049787 countsByYear W21570497872012 @default.
- W2157049787 countsByYear W21570497872013 @default.
- W2157049787 countsByYear W21570497872014 @default.
- W2157049787 countsByYear W21570497872015 @default.
- W2157049787 countsByYear W21570497872016 @default.
- W2157049787 countsByYear W21570497872017 @default.
- W2157049787 countsByYear W21570497872018 @default.
- W2157049787 crossrefType "journal-article" @default.
- W2157049787 hasAuthorship W2157049787A5000546523 @default.
- W2157049787 hasAuthorship W2157049787A5008324975 @default.
- W2157049787 hasAuthorship W2157049787A5010600188 @default.
- W2157049787 hasAuthorship W2157049787A5049619456 @default.
- W2157049787 hasConcept C126322002 @default.
- W2157049787 hasConcept C126894567 @default.
- W2157049787 hasConcept C141071460 @default.
- W2157049787 hasConcept C142225936 @default.
- W2157049787 hasConcept C158846371 @default.
- W2157049787 hasConcept C159641895 @default.
- W2157049787 hasConcept C2776634560 @default.
- W2157049787 hasConcept C2780091579 @default.
- W2157049787 hasConcept C2781073237 @default.
- W2157049787 hasConcept C2911091166 @default.
- W2157049787 hasConcept C42219234 @default.
- W2157049787 hasConcept C50156730 @default.
- W2157049787 hasConcept C529278444 @default.
- W2157049787 hasConcept C541997718 @default.
- W2157049787 hasConcept C71924100 @default.
- W2157049787 hasConceptScore W2157049787C126322002 @default.
- W2157049787 hasConceptScore W2157049787C126894567 @default.
- W2157049787 hasConceptScore W2157049787C141071460 @default.
- W2157049787 hasConceptScore W2157049787C142225936 @default.
- W2157049787 hasConceptScore W2157049787C158846371 @default.
- W2157049787 hasConceptScore W2157049787C159641895 @default.
- W2157049787 hasConceptScore W2157049787C2776634560 @default.
- W2157049787 hasConceptScore W2157049787C2780091579 @default.
- W2157049787 hasConceptScore W2157049787C2781073237 @default.
- W2157049787 hasConceptScore W2157049787C2911091166 @default.
- W2157049787 hasConceptScore W2157049787C42219234 @default.
- W2157049787 hasConceptScore W2157049787C50156730 @default.
- W2157049787 hasConceptScore W2157049787C529278444 @default.
- W2157049787 hasConceptScore W2157049787C541997718 @default.
- W2157049787 hasConceptScore W2157049787C71924100 @default.
- W2157049787 hasIssue "1" @default.
- W2157049787 hasLocation W21570497871 @default.
- W2157049787 hasLocation W21570497872 @default.
- W2157049787 hasOpenAccess W2157049787 @default.
- W2157049787 hasPrimaryLocation W21570497871 @default.
- W2157049787 hasRelatedWork W1978393366 @default.
- W2157049787 hasRelatedWork W2035471303 @default.
- W2157049787 hasRelatedWork W2038210690 @default.
- W2157049787 hasRelatedWork W2046380573 @default.
- W2157049787 hasRelatedWork W2064839307 @default.
- W2157049787 hasRelatedWork W2104233013 @default.
- W2157049787 hasRelatedWork W2176341824 @default.
- W2157049787 hasRelatedWork W2326573810 @default.
- W2157049787 hasRelatedWork W2411218156 @default.
- W2157049787 hasRelatedWork W2417656441 @default.
- W2157049787 hasVolume "41" @default.
- W2157049787 isParatext "false" @default.
- W2157049787 isRetracted "false" @default.
- W2157049787 magId "2157049787" @default.
- W2157049787 workType "article" @default.