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- W2157118250 startingPage "21" @default.
- W2157118250 abstract "Summary Leptin and ghrelin are two hormones that have been recognized to have a major influence on energy balance. Leptin is a mediator of long‐term regulation of energy balance, suppressing food intake and thereby inducing weight loss. Ghrelin on the other hand is a fast‐acting hormone, seemingly playing a role in meal initiation. As a growing number of people suffer from obesity, understanding the mechanisms by which various hormones and neurotransmitters have influence on energy balance has been a subject of intensive research. In obese subjects the circulating level of the anorexigenic hormone leptin is increased, whereas surprisingly, the level of the orexigenic hormone ghrelin is decreased. It is now established that obese patients are leptin‐resistant. However, the manner in which both the leptin and ghrelin systems contribute to the development or maintenance of obesity is as yet not clear. The purpose of this review is to provide background information on the leptin and ghrelin hormones, their role in food intake and body weight in humans, and their mechanism of action. Possible abnormalities in the leptin and ghrelin systems that may contribute to the development of obesity will be mentioned. In addition, the potentials of leptin and ghrelin as drug targets will be discussed. Finally, the influence of the diet on leptin and ghrelin secretion and functioning will be described." @default.
- W2157118250 created "2016-06-24" @default.
- W2157118250 creator A5027044143 @default.
- W2157118250 creator A5038606885 @default.
- W2157118250 creator A5060701422 @default.
- W2157118250 date "2006-08-24" @default.
- W2157118250 modified "2023-10-15" @default.
- W2157118250 title "The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review" @default.
- W2157118250 cites W1490643348 @default.
- W2157118250 cites W1512875938 @default.
- W2157118250 cites W1527986744 @default.
- W2157118250 cites W154047992 @default.
- W2157118250 cites W1551216731 @default.
- W2157118250 cites W1590709474 @default.
- W2157118250 cites W1596409175 @default.
- W2157118250 cites W1616806865 @default.
- W2157118250 cites W1617674044 @default.
- W2157118250 cites W1637971961 @default.
- W2157118250 cites W1639930240 @default.
- W2157118250 cites W1885840513 @default.
- W2157118250 cites W1900852307 @default.
- W2157118250 cites W1964081706 @default.
- W2157118250 cites W1964863934 @default.
- W2157118250 cites W1964865909 @default.
- W2157118250 cites W1965627493 @default.
- W2157118250 cites W1967501438 @default.
- W2157118250 cites W1971002481 @default.
- W2157118250 cites W1971692114 @default.
- W2157118250 cites W1975390269 @default.
- W2157118250 cites W1977954577 @default.
- W2157118250 cites W1979051675 @default.
- W2157118250 cites W1979879251 @default.
- W2157118250 cites W1981547049 @default.
- W2157118250 cites W1985071684 @default.
- W2157118250 cites W1985328809 @default.
- W2157118250 cites W1986676233 @default.
- W2157118250 cites W1987049214 @default.
- W2157118250 cites W1989237770 @default.
- W2157118250 cites W1989343508 @default.
- W2157118250 cites W1990095603 @default.
- W2157118250 cites W1991057455 @default.
- W2157118250 cites W1992271389 @default.
- W2157118250 cites W1992328870 @default.
- W2157118250 cites W1992532321 @default.
- W2157118250 cites W1995734405 @default.
- W2157118250 cites W1996713062 @default.
- W2157118250 cites W1998991189 @default.
- W2157118250 cites W2005409308 @default.
- W2157118250 cites W2006011837 @default.
- W2157118250 cites W2006190738 @default.
- W2157118250 cites W2007576186 @default.
- W2157118250 cites W2009968514 @default.
- W2157118250 cites W2010087093 @default.
- W2157118250 cites W2014093920 @default.
- W2157118250 cites W2014101527 @default.
- W2157118250 cites W2015174242 @default.
- W2157118250 cites W2016525263 @default.
- W2157118250 cites W2021052947 @default.
- W2157118250 cites W2024734221 @default.
- W2157118250 cites W2026200282 @default.
- W2157118250 cites W2027427622 @default.
- W2157118250 cites W2028852111 @default.
- W2157118250 cites W2031585557 @default.
- W2157118250 cites W2031677322 @default.
- W2157118250 cites W2036385198 @default.
- W2157118250 cites W2037328290 @default.
- W2157118250 cites W2041416783 @default.
- W2157118250 cites W2041872947 @default.
- W2157118250 cites W2042535492 @default.
- W2157118250 cites W2044484295 @default.
- W2157118250 cites W2048078221 @default.
- W2157118250 cites W2048194663 @default.
- W2157118250 cites W2050931629 @default.
- W2157118250 cites W2051138072 @default.
- W2157118250 cites W2051138087 @default.
- W2157118250 cites W2052743140 @default.
- W2157118250 cites W2053321990 @default.
- W2157118250 cites W2053426841 @default.
- W2157118250 cites W2055843904 @default.
- W2157118250 cites W2056383195 @default.
- W2157118250 cites W2057919982 @default.
- W2157118250 cites W2060682066 @default.
- W2157118250 cites W2061337207 @default.
- W2157118250 cites W2061549704 @default.
- W2157118250 cites W2063052824 @default.
- W2157118250 cites W2069156113 @default.
- W2157118250 cites W2069302715 @default.
- W2157118250 cites W2069854515 @default.
- W2157118250 cites W2070813616 @default.
- W2157118250 cites W2073738204 @default.
- W2157118250 cites W2076256003 @default.
- W2157118250 cites W2081465427 @default.
- W2157118250 cites W2081494990 @default.
- W2157118250 cites W2082296856 @default.
- W2157118250 cites W2085218910 @default.
- W2157118250 cites W2087482176 @default.
- W2157118250 cites W2088666203 @default.
- W2157118250 cites W2095124986 @default.