FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157178278> ?p ?o ?g. }

• W2157178278 endingPage "383" @default.
• W2157178278 startingPage "377" @default.
• W2157178278 abstract "The cyclic nucleotide phosphodiesterase (PDE) activities were studied in a nerve ending fraction from bovine neural lobes. Most of the activity was particulate and unaffected by calcium. Lineweaver-Burk plots for this fraction showed negative cooperativity with apparent Km values for cyclic AMP of 11 microM and for cyclic GMP of 4 microM. The soluble activities for both cyclic nucleotides were activated by calcium and inhibited by calmodulin-binding drugs (trifluoperazine and calmidazolium). The apparent Km values were 50 microM for cyclic AMP and 20 microM for cyclic GMP for the soluble activities. Sucrose density gradients resolved the soluble activities into two peaks. The activity with the higher sedimentation rate (MW 122,000 daltons) hydrolysed both cyclic nucleotides and was calcium-calmodulin-dependent. The other peak (MW 47,000 daltons) had a higher affinity for cyclic AMP than for cyclic GMP and was calcium-independent. Solubilized particulate activities gave two main peaks on the density gradient, both calcium-independent. One was mainly for cyclic AMP (MW 47,000 daltons) and the other mainly for cyclic GMP (MW 133,000 daltons). The function of PDEs in relation to secretion was discussed." @default.
• W2157178278 created "2016-06-24" @default.
• W2157178278 creator A5025807977 @default.
• W2157178278 creator A5082364334 @default.
• W2157178278 creator A5085966304 @default.
• W2157178278 date "1984-02-01" @default.
• W2157178278 modified "2023-09-26" @default.
• W2157178278 title "Phosphodiesterase Activities for Cyclic Nucleotides in Nerve Endings from the Bovine Posterior Pituitary Gland" @default.
• W2157178278 cites W1533000163 @default.
• W2157178278 cites W1535151692 @default.
• W2157178278 cites W1567413936 @default.
• W2157178278 cites W1602784471 @default.
• W2157178278 cites W1611482599 @default.
• W2157178278 cites W1775749144 @default.
• W2157178278 cites W1968612089 @default.
• W2157178278 cites W1978202577 @default.
• W2157178278 cites W1989977352 @default.
• W2157178278 cites W2007668225 @default.
• W2157178278 cites W2010424836 @default.
• W2157178278 cites W2014898526 @default.
• W2157178278 cites W2026288575 @default.
• W2157178278 cites W2028519419 @default.
• W2157178278 cites W2028562375 @default.
• W2157178278 cites W2029169169 @default.
• W2157178278 cites W2030542053 @default.
• W2157178278 cites W2047404335 @default.
• W2157178278 cites W2064054581 @default.
• W2157178278 cites W2072778915 @default.
• W2157178278 cites W2079709658 @default.
• W2157178278 cites W2085873925 @default.
• W2157178278 cites W2137812689 @default.
• W2157178278 cites W2138745918 @default.
• W2157178278 cites W2139560504 @default.
• W2157178278 cites W2167872701 @default.
• W2157178278 cites W2169090652 @default.
• W2157178278 cites W2316953031 @default.
• W2157178278 cites W2474609795 @default.
• W2157178278 cites W2764534150 @default.
• W2157178278 cites W4293281627 @default.
• W2157178278 doi "https://doi.org/10.1111/j.1471-4159.1984.tb02688.x" @default.
• W2157178278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6319599" @default.
• W2157178278 hasPublicationYear "1984" @default.
• W2157178278 type Work @default.
• W2157178278 sameAs 2157178278 @default.
• W2157178278 citedByCount "4" @default.
• W2157178278 crossrefType "journal-article" @default.
• W2157178278 hasAuthorship W2157178278A5025807977 @default.
• W2157178278 hasAuthorship W2157178278A5082364334 @default.
• W2157178278 hasAuthorship W2157178278A5085966304 @default.
• W2157178278 hasConcept C104317684 @default.
• W2157178278 hasConcept C116073593 @default.
• W2157178278 hasConcept C12554922 @default.
• W2157178278 hasConcept C134018914 @default.
• W2157178278 hasConcept C136357698 @default.
• W2157178278 hasConcept C166014724 @default.
• W2157178278 hasConcept C178790620 @default.
• W2157178278 hasConcept C181199279 @default.
• W2157178278 hasConcept C185592680 @default.
• W2157178278 hasConcept C202751555 @default.
• W2157178278 hasConcept C2775891158 @default.
• W2157178278 hasConcept C2778524494 @default.
• W2157178278 hasConcept C2780215583 @default.
• W2157178278 hasConcept C29688787 @default.
• W2157178278 hasConcept C512185932 @default.
• W2157178278 hasConcept C519063684 @default.
• W2157178278 hasConcept C55493867 @default.
• W2157178278 hasConcept C62826618 @default.
• W2157178278 hasConcept C86803240 @default.
• W2157178278 hasConceptScore W2157178278C104317684 @default.
• W2157178278 hasConceptScore W2157178278C116073593 @default.
• W2157178278 hasConceptScore W2157178278C12554922 @default.
• W2157178278 hasConceptScore W2157178278C134018914 @default.
• W2157178278 hasConceptScore W2157178278C136357698 @default.
• W2157178278 hasConceptScore W2157178278C166014724 @default.
• W2157178278 hasConceptScore W2157178278C178790620 @default.
• W2157178278 hasConceptScore W2157178278C181199279 @default.
• W2157178278 hasConceptScore W2157178278C185592680 @default.
• W2157178278 hasConceptScore W2157178278C202751555 @default.
• W2157178278 hasConceptScore W2157178278C2775891158 @default.
• W2157178278 hasConceptScore W2157178278C2778524494 @default.
• W2157178278 hasConceptScore W2157178278C2780215583 @default.
• W2157178278 hasConceptScore W2157178278C29688787 @default.
• W2157178278 hasConceptScore W2157178278C512185932 @default.
• W2157178278 hasConceptScore W2157178278C519063684 @default.
• W2157178278 hasConceptScore W2157178278C55493867 @default.
• W2157178278 hasConceptScore W2157178278C62826618 @default.
• W2157178278 hasConceptScore W2157178278C86803240 @default.
• W2157178278 hasIssue "2" @default.
• W2157178278 hasLocation W21571782781 @default.
• W2157178278 hasLocation W21571782782 @default.
• W2157178278 hasOpenAccess W2157178278 @default.
• W2157178278 hasPrimaryLocation W21571782781 @default.
• W2157178278 hasRelatedWork W129545540 @default.
• W2157178278 hasRelatedWork W2025474323 @default.
• W2157178278 hasRelatedWork W2047721665 @default.
• W2157178278 hasRelatedWork W2056859235 @default.
• W2157178278 hasRelatedWork W2062740392 @default.
• W2157178278 hasRelatedWork W2080048815 @default.

• next