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- W2157188884 abstract "The aim was to demonstrate functional properties of transplanted histologically normal photoreceptors. Subretinal intact-sheet transplants of fetal E17–E20 rat retinas to light-damaged albino rat eyes were fixed in light or dark, 2 to 42 weeks after transplantation, and stained immunohistochemically for certain phototransduction proteins. In light adapted transplants, transducin was predominantly found in inner segments of parallel-organized photoreceptors. Transducin shifted to the outer segments with dark-adaptation. S-antigen distribution was opposite to transducin. Rhodopsin distribution did not change. The shift of signal transduction proteins correlated to the light conditions indicates that normal phototransduction processes were established in photoreceptors of transplanted retinal sheets." @default.
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- W2157188884 date "1999-07-01" @default.
- W2157188884 modified "2023-10-10" @default.
- W2157188884 title "Photoreceptor function of retinal transplants implicated by light-dark shift of S-antigen and rod transducin" @default.
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- W2157188884 doi "https://doi.org/10.1016/s0042-6989(98)00326-5" @default.
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