FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157227735> ?p ?o ?g. }

• W2157227735 endingPage "336" @default.
• W2157227735 startingPage "328" @default.
• W2157227735 abstract "The CLAVATA signaling pathway is a key component of the network that controls stem cell renewal and differentiation in Arabidopsis thaliana. CLAVATA3 (CLV3) is a post-translationally arabinosylated secreted peptide signal that regulates WUSHEL (WUS) transcription to affect the balance of stem cell differentiation and proliferation in the shoot apical meristem (SAM). Known membrane-localized receptors involved in the perception of CLV3 signaling include CLV1, the CLV2/CORYNE (CRN) complex and RPK2. The CLV3 peptide can directly bind to CLV1; however, it is unclear whether the CLV3 peptide directly binds to CLV2 or RPK2. In this study, we re-evaluated the direct interaction between CLV3 and its receptors by photoaffinity labeling with photoactivatable arabinosylated CLV3. We showed that CLV2 and RPK2 exhibited no direct binding to the CLV3 peptide. Further analysis showed that the receptor kinase BAM1 directly binds the CLV3 peptide. A loss-of-function clv1 bam1 double mutant exhibited a large number of stem cells that accumulated in the SAM and was insensitive to exogenous treatment with the arabinosylated CLV3 peptide. WUS gene transcripts were up-regulated, and the region of WUS expression was enlarged at the SAM in the clv1 bam1 double mutant. These results indicate that CLV1 and BAM1 are direct receptors that are sufficient to affect the regulatory network controlling stem cell number in the SAM. In contrast, the CLV2/CRN complex and RPK2 are not involved in direct ligand interactions but may act as co-receptors." @default.
• W2157227735 created "2016-06-24" @default.
• W2157227735 creator A5006770831 @default.
• W2157227735 creator A5014449606 @default.
• W2157227735 date "2015-04-01" @default.
• W2157227735 modified "2023-10-18" @default.
• W2157227735 title "Reevaluation of the CLV3-receptor interaction in the shoot apical meristem: dissection of the CLV3 signaling pathway from a direct ligand-binding point of view" @default.
• W2157227735 cites W1989726653 @default.
• W2157227735 cites W1992353594 @default.
• W2157227735 cites W2002507269 @default.
• W2157227735 cites W2023230492 @default.
• W2157227735 cites W2031310524 @default.
• W2157227735 cites W2044217417 @default.
• W2157227735 cites W2046103512 @default.
• W2157227735 cites W2058229105 @default.
• W2157227735 cites W2080992822 @default.
• W2157227735 cites W2091567597 @default.
• W2157227735 cites W2092212990 @default.
• W2157227735 cites W2104159973 @default.
• W2157227735 cites W2104945674 @default.
• W2157227735 cites W2115598343 @default.
• W2157227735 cites W2116122104 @default.
• W2157227735 cites W2118185000 @default.
• W2157227735 cites W2121182653 @default.
• W2157227735 cites W2135202770 @default.
• W2157227735 cites W2136231175 @default.
• W2157227735 cites W2136341461 @default.
• W2157227735 cites W2147090904 @default.
• W2157227735 cites W2156108266 @default.
• W2157227735 cites W2158260463 @default.
• W2157227735 cites W2159341467 @default.
• W2157227735 cites W2159807609 @default.
• W2157227735 cites W2161060432 @default.
• W2157227735 cites W2161460195 @default.
• W2157227735 cites W2167019069 @default.
• W2157227735 cites W2169393691 @default.
• W2157227735 cites W4212814752 @default.
• W2157227735 doi "https://doi.org/10.1111/tpj.12817" @default.
• W2157227735 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25754504" @default.
• W2157227735 hasPublicationYear "2015" @default.
• W2157227735 type Work @default.
• W2157227735 sameAs 2157227735 @default.
• W2157227735 citedByCount "107" @default.
• W2157227735 countsByYear W21572277352015 @default.
• W2157227735 countsByYear W21572277352016 @default.
• W2157227735 countsByYear W21572277352017 @default.
• W2157227735 countsByYear W21572277352018 @default.
• W2157227735 countsByYear W21572277352019 @default.
• W2157227735 countsByYear W21572277352020 @default.
• W2157227735 countsByYear W21572277352021 @default.
• W2157227735 countsByYear W21572277352022 @default.
• W2157227735 countsByYear W21572277352023 @default.
• W2157227735 crossrefType "journal-article" @default.
• W2157227735 hasAuthorship W2157227735A5006770831 @default.
• W2157227735 hasAuthorship W2157227735A5014449606 @default.
• W2157227735 hasBestOaLocation W21572277351 @default.
• W2157227735 hasConcept C104317684 @default.
• W2157227735 hasConcept C126021549 @default.
• W2157227735 hasConcept C143065580 @default.
• W2157227735 hasConcept C1491633281 @default.
• W2157227735 hasConcept C170493617 @default.
• W2157227735 hasConcept C2775988993 @default.
• W2157227735 hasConcept C2779281246 @default.
• W2157227735 hasConcept C2779491563 @default.
• W2157227735 hasConcept C55493867 @default.
• W2157227735 hasConcept C62478195 @default.
• W2157227735 hasConcept C70721500 @default.
• W2157227735 hasConcept C86803240 @default.
• W2157227735 hasConcept C95444343 @default.
• W2157227735 hasConceptScore W2157227735C104317684 @default.
• W2157227735 hasConceptScore W2157227735C126021549 @default.
• W2157227735 hasConceptScore W2157227735C143065580 @default.
• W2157227735 hasConceptScore W2157227735C1491633281 @default.
• W2157227735 hasConceptScore W2157227735C170493617 @default.
• W2157227735 hasConceptScore W2157227735C2775988993 @default.
• W2157227735 hasConceptScore W2157227735C2779281246 @default.
• W2157227735 hasConceptScore W2157227735C2779491563 @default.
• W2157227735 hasConceptScore W2157227735C55493867 @default.
• W2157227735 hasConceptScore W2157227735C62478195 @default.
• W2157227735 hasConceptScore W2157227735C70721500 @default.
• W2157227735 hasConceptScore W2157227735C86803240 @default.
• W2157227735 hasConceptScore W2157227735C95444343 @default.
• W2157227735 hasIssue "2" @default.
• W2157227735 hasLocation W21572277351 @default.
• W2157227735 hasLocation W21572277352 @default.
• W2157227735 hasOpenAccess W2157227735 @default.
• W2157227735 hasPrimaryLocation W21572277351 @default.
• W2157227735 hasRelatedWork W1927220190 @default.
• W2157227735 hasRelatedWork W1966477955 @default.
• W2157227735 hasRelatedWork W2001866200 @default.
• W2157227735 hasRelatedWork W2040764540 @default.
• W2157227735 hasRelatedWork W2085576066 @default.
• W2157227735 hasRelatedWork W2371524367 @default.
• W2157227735 hasRelatedWork W2400294522 @default.
• W2157227735 hasRelatedWork W2730214156 @default.
• W2157227735 hasRelatedWork W2947452046 @default.
• W2157227735 hasRelatedWork W4289521774 @default.
• W2157227735 hasVolume "82" @default.

• next