Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157300795> ?p ?o ?g. }
- W2157300795 endingPage "1261" @default.
- W2157300795 startingPage "1247" @default.
- W2157300795 abstract "Abstract Mitofilin proteins are crucial organizers of mitochondrial architecture. They are located in the inner mitochondrial membrane and interact with several protein complexes of the outer membrane, thereby generating contact sites between the two membrane systems of mitochondria. Within the inner membrane, mitofilins are part of hetero-oligomeric protein complexes that have been termed the mitochondrial inner membrane organizing system (MINOS). MINOS integrity is required for the maintenance of the characteristic morphology of the inner mitochondrial membrane, with an inner boundary region closely apposed to the outer membrane and cristae membranes, which form large tubular invaginations that protrude into the mitochondrial matrix and harbor the enzyme complexes of the oxidative phosphorylation machinery. MINOS deficiency comes along with a loss of crista junction structures and the detachment of cristae from the inner boundary membrane. MINOS has been conserved in evolution from unicellular eukaryotes to humans, where alterations of MINOS subunits are associated with multiple pathological conditions." @default.
- W2157300795 created "2016-06-24" @default.
- W2157300795 creator A5000851275 @default.
- W2157300795 creator A5013861328 @default.
- W2157300795 creator A5014217628 @default.
- W2157300795 creator A5048982092 @default.
- W2157300795 creator A5085249551 @default.
- W2157300795 creator A5087737199 @default.
- W2157300795 date "2012-10-11" @default.
- W2157300795 modified "2023-10-11" @default.
- W2157300795 title "Mitofilin complexes: conserved organizers of mitochondrial membrane architecture" @default.
- W2157300795 cites W1932855763 @default.
- W2157300795 cites W1964867682 @default.
- W2157300795 cites W1967445833 @default.
- W2157300795 cites W1970243208 @default.
- W2157300795 cites W1970393644 @default.
- W2157300795 cites W1971045545 @default.
- W2157300795 cites W1974750801 @default.
- W2157300795 cites W1976391651 @default.
- W2157300795 cites W1978268445 @default.
- W2157300795 cites W1978382819 @default.
- W2157300795 cites W1978813419 @default.
- W2157300795 cites W1981168617 @default.
- W2157300795 cites W1991003837 @default.
- W2157300795 cites W1994373739 @default.
- W2157300795 cites W1996476714 @default.
- W2157300795 cites W1997527771 @default.
- W2157300795 cites W2002364392 @default.
- W2157300795 cites W2003562213 @default.
- W2157300795 cites W2010526388 @default.
- W2157300795 cites W2010925630 @default.
- W2157300795 cites W2011614492 @default.
- W2157300795 cites W2012014117 @default.
- W2157300795 cites W2016344599 @default.
- W2157300795 cites W2020432830 @default.
- W2157300795 cites W2021138475 @default.
- W2157300795 cites W2024595059 @default.
- W2157300795 cites W2032179615 @default.
- W2157300795 cites W2032234589 @default.
- W2157300795 cites W2033758544 @default.
- W2157300795 cites W2039276913 @default.
- W2157300795 cites W2039409049 @default.
- W2157300795 cites W2039413161 @default.
- W2157300795 cites W2039551144 @default.
- W2157300795 cites W2045085957 @default.
- W2157300795 cites W2046211197 @default.
- W2157300795 cites W2049150429 @default.
- W2157300795 cites W2049576864 @default.
- W2157300795 cites W2049733177 @default.
- W2157300795 cites W2051342341 @default.
- W2157300795 cites W2055572268 @default.
- W2157300795 cites W2058153670 @default.
- W2157300795 cites W2071337010 @default.
- W2157300795 cites W2073574119 @default.
- W2157300795 cites W2077550333 @default.
- W2157300795 cites W2082521885 @default.
- W2157300795 cites W2083998249 @default.
- W2157300795 cites W2085229930 @default.
- W2157300795 cites W2086735769 @default.
- W2157300795 cites W2089700857 @default.
- W2157300795 cites W2090734611 @default.
- W2157300795 cites W2091489629 @default.
- W2157300795 cites W2091575008 @default.
- W2157300795 cites W2092725897 @default.
- W2157300795 cites W2092899472 @default.
- W2157300795 cites W2093226550 @default.
- W2157300795 cites W2093921916 @default.
- W2157300795 cites W2094113524 @default.
- W2157300795 cites W2096321546 @default.
- W2157300795 cites W2098143955 @default.
- W2157300795 cites W2100617050 @default.
- W2157300795 cites W2101112886 @default.
- W2157300795 cites W2101300328 @default.
- W2157300795 cites W2101580077 @default.
- W2157300795 cites W2107847140 @default.
- W2157300795 cites W2109038505 @default.
- W2157300795 cites W2110547951 @default.
- W2157300795 cites W2114065979 @default.
- W2157300795 cites W2115944704 @default.
- W2157300795 cites W2116034532 @default.
- W2157300795 cites W2121966499 @default.
- W2157300795 cites W2123570806 @default.
- W2157300795 cites W2124895002 @default.
- W2157300795 cites W2126628065 @default.
- W2157300795 cites W2126932378 @default.
- W2157300795 cites W2127271204 @default.
- W2157300795 cites W2128055033 @default.
- W2157300795 cites W2128916568 @default.
- W2157300795 cites W2130758099 @default.
- W2157300795 cites W2134802476 @default.
- W2157300795 cites W2135167542 @default.
- W2157300795 cites W2135772494 @default.
- W2157300795 cites W2137250940 @default.
- W2157300795 cites W2137564359 @default.
- W2157300795 cites W2139996682 @default.
- W2157300795 cites W2142852559 @default.
- W2157300795 cites W2150164439 @default.
- W2157300795 cites W2151698573 @default.