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- W2157302214 endingPage "365" @default.
- W2157302214 startingPage "351" @default.
- W2157302214 abstract "Thyroid hormone is a critical regulator of growth, development, and metabolism in virtually all tissues, and altered thyroid status affects many organs and systems. Although for many years testis has been regarded as a thyroid hormone unresponsive organ, it is now evident that thyroid hormone plays an important role in testicular development and function. A considerable amount of data show that thyroid hormone influences steroidogenesis as well as spermatogenesis. The involvement of tri-iodothyronine (T 3 ) in the control of Sertoli cell proliferation and functional maturation is widely accepted, as well as its role in postnatal Leydig cell differentiation and steroidogenesis. The presence of thyroid hormone receptors in testicular cells throughout development and in adulthood implies that T 3 may act directly on these cells to bring about its effects. Several recent studies have employed different methodologies and techniques in an attempt to understand the mechanisms underlying thyroid hormone effects on testicular cells. The current review aims at presenting an updated picture of the recent advances made regarding the role of thyroid hormones in male gonadal function." @default.
- W2157302214 created "2016-06-24" @default.
- W2157302214 creator A5007399848 @default.
- W2157302214 creator A5016350528 @default.
- W2157302214 creator A5067415891 @default.
- W2157302214 date "2008-08-26" @default.
- W2157302214 modified "2023-10-09" @default.
- W2157302214 title "The role of thyroid hormone in testicular development and function" @default.
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