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- W2157314897 abstract "Antidiabetic and beta cell-protection activities of purple corn anthocyanins (PCA) were examined in pancreatic beta cell culture and db/db mice. Only PCA among several plant anthocyanins and polyphenols showed insulin secretion activity in culture of HIT-T15 cells. PCA had excellent antihyperglycemic activity (in terms of blood glucose level and OGTT) and HbA1c-decreasing activity when compared with glimepiride, a sulfonylurea in db/db mice. In addition, PCA showed efficient protection activity of pancreatic beta cell from cell death in HIT-T15 cell culture and db/db mice. The result showed that PCA had antidiabetic and beta cell-protection activities in pancreatic beta cell culture and db/db mice." @default.
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- W2157314897 date "2013-07-31" @default.
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- W2157314897 title "Antidiabetic and Beta Cell-Protection Activities of Purple Corn Anthocyanins" @default.
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- W2157314897 doi "https://doi.org/10.4062/biomolther.2013.016" @default.
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