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• W2157339938 abstract "Two new dimeric sterols, manadosterols A (1) and B (2), were isolated from the marine sponge Lissodendryx fibrosa collected in Indonesia. The two compounds are comprised of two sulfonated sterol cores connected through the respective side chains. Manadosterols A (1) and B (2) inhibited the Ubc13-Uev1A interaction with IC50 values of 0.09 and 0.13 μM, respectively. They are the second and third natural compounds showing inhibitory activities against the Ubc13–Uev1A interaction and are more potent than leucettamol A (IC50, 106 μM), the first such inhibitor, isolated from another marine sponge." @default.
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• W2157339938 date "2012-08-08" @default.
• W2157339938 modified "2023-09-30" @default.
• W2157339938 title "Manadosterols A and B, Sulfonated Sterol Dimers Inhibiting the Ubc13–Uev1A Interaction, Isolated from the Marine Sponge <i>Lissodendryx fibrosa</i>" @default.
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• W2157339938 doi "https://doi.org/10.1021/np300352u" @default.
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