Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157421338> ?p ?o ?g. }
- W2157421338 endingPage "995" @default.
- W2157421338 startingPage "987" @default.
- W2157421338 abstract "Trophozoites of Entamoeba histolytica HM-1:IMSS become less virulent after long-term maintenance in axenic cultures. The factors responsible for the loss of virulence during in vitro cultivation remain unclear. However, it is known that in vitro cultivation of amoeba in culture medium supplemented with cholesterol restores their virulence. In this study, we analyzed the effect of adding phosphatidylcholine–cholesterol (PC–Chol) liposomes to the culture medium and evaluated the effect of this lipid on various biochemical and biological functions of E. histolytica HM-1:IMSS in terms of its virulence. The addition of PC–Chol liposomes to the culture medium maintained the virulence of these parasites against hamster liver at the same level as the original virulent E. histolytica strain, even though these amoebae were maintained without passage through hamster liver for 18 months. The trophozoites also showed increased endocytosis, erythrophagocytosis, and carbohydrate residue expression on the amoebic surface. Protease activities were also modified by the presence of cholesterol in the culture medium. These findings indicate the capacity of cholesterol to preserve amoeba virulence and provide an alternative method for the maintenance of virulent E. histolytica trophozoites without the need for in vivo procedures." @default.
- W2157421338 created "2016-06-24" @default.
- W2157421338 creator A5026585732 @default.
- W2157421338 creator A5049121669 @default.
- W2157421338 creator A5060947361 @default.
- W2157421338 creator A5082776061 @default.
- W2157421338 creator A5086149383 @default.
- W2157421338 creator A5088709113 @default.
- W2157421338 date "2010-12-01" @default.
- W2157421338 modified "2023-10-03" @default.
- W2157421338 title "Effect of phosphatidylcholine–cholesterol liposomes on Entamoeba histolytica virulence" @default.
- W2157421338 cites W1970882240 @default.
- W2157421338 cites W1974254036 @default.
- W2157421338 cites W1988408072 @default.
- W2157421338 cites W2000661169 @default.
- W2157421338 cites W2002045679 @default.
- W2157421338 cites W2015490622 @default.
- W2157421338 cites W2016321141 @default.
- W2157421338 cites W2019909856 @default.
- W2157421338 cites W2023490858 @default.
- W2157421338 cites W2027123731 @default.
- W2157421338 cites W2028270709 @default.
- W2157421338 cites W2032630270 @default.
- W2157421338 cites W2042581118 @default.
- W2157421338 cites W2045186739 @default.
- W2157421338 cites W2046365038 @default.
- W2157421338 cites W2047356597 @default.
- W2157421338 cites W2049138856 @default.
- W2157421338 cites W2060266279 @default.
- W2157421338 cites W2064307043 @default.
- W2157421338 cites W2070309391 @default.
- W2157421338 cites W2076246604 @default.
- W2157421338 cites W2077752559 @default.
- W2157421338 cites W2097046100 @default.
- W2157421338 cites W2107132396 @default.
- W2157421338 cites W2111268509 @default.
- W2157421338 cites W2114302400 @default.
- W2157421338 cites W2119247852 @default.
- W2157421338 cites W2122797441 @default.
- W2157421338 cites W2133858553 @default.
- W2157421338 cites W2137974993 @default.
- W2157421338 cites W2140238241 @default.
- W2157421338 cites W2143302258 @default.
- W2157421338 cites W2162351483 @default.
- W2157421338 cites W2170128395 @default.
- W2157421338 cites W2182364176 @default.
- W2157421338 cites W2335407238 @default.
- W2157421338 cites W2336308466 @default.
- W2157421338 cites W2395925423 @default.
- W2157421338 cites W2414502086 @default.
- W2157421338 cites W4293247451 @default.
- W2157421338 cites W4300705170 @default.
- W2157421338 cites W625855691 @default.
- W2157421338 doi "https://doi.org/10.1139/w10-088" @default.
- W2157421338 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21164568" @default.
- W2157421338 hasPublicationYear "2010" @default.
- W2157421338 type Work @default.
- W2157421338 sameAs 2157421338 @default.
- W2157421338 citedByCount "16" @default.
- W2157421338 countsByYear W21574213382012 @default.
- W2157421338 countsByYear W21574213382013 @default.
- W2157421338 countsByYear W21574213382014 @default.
- W2157421338 countsByYear W21574213382015 @default.
- W2157421338 countsByYear W21574213382016 @default.
- W2157421338 countsByYear W21574213382018 @default.
- W2157421338 countsByYear W21574213382019 @default.
- W2157421338 countsByYear W21574213382020 @default.
- W2157421338 countsByYear W21574213382021 @default.
- W2157421338 crossrefType "journal-article" @default.
- W2157421338 hasAuthorship W2157421338A5026585732 @default.
- W2157421338 hasAuthorship W2157421338A5049121669 @default.
- W2157421338 hasAuthorship W2157421338A5060947361 @default.
- W2157421338 hasAuthorship W2157421338A5082776061 @default.
- W2157421338 hasAuthorship W2157421338A5086149383 @default.
- W2157421338 hasAuthorship W2157421338A5088709113 @default.
- W2157421338 hasConcept C104317684 @default.
- W2157421338 hasConcept C150903083 @default.
- W2157421338 hasConcept C153911025 @default.
- W2157421338 hasConcept C160448771 @default.
- W2157421338 hasConcept C202751555 @default.
- W2157421338 hasConcept C207001950 @default.
- W2157421338 hasConcept C2776867272 @default.
- W2157421338 hasConcept C2778163477 @default.
- W2157421338 hasConcept C2778265057 @default.
- W2157421338 hasConcept C2778575167 @default.
- W2157421338 hasConcept C523546767 @default.
- W2157421338 hasConcept C54355233 @default.
- W2157421338 hasConcept C55493867 @default.
- W2157421338 hasConcept C60987743 @default.
- W2157421338 hasConcept C86803240 @default.
- W2157421338 hasConcept C89423630 @default.
- W2157421338 hasConceptScore W2157421338C104317684 @default.
- W2157421338 hasConceptScore W2157421338C150903083 @default.
- W2157421338 hasConceptScore W2157421338C153911025 @default.
- W2157421338 hasConceptScore W2157421338C160448771 @default.
- W2157421338 hasConceptScore W2157421338C202751555 @default.
- W2157421338 hasConceptScore W2157421338C207001950 @default.
- W2157421338 hasConceptScore W2157421338C2776867272 @default.