FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157426972> ?p ?o ?g. }

• W2157426972 endingPage "7" @default.
• W2157426972 startingPage "1" @default.
• W2157426972 abstract "Objective. To study the effects of estrogen on colon polyp formation, proliferation, and angiogenesis on a rat model of colon cancer induced by dimethylhydrazine (DMH). Methods. Thirty-six female ovariectomized (OVX) rats were randomly divided into 3 groups: (I) control group (administrated with vehicles weekly), (II) DMH group (administrated with DMH weekly), and (III) DMH + E 2 group (administrated with DMH and 17<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mi>β</mml:mi></mml:mrow></mml:math>-estradiol weekly). The incidence, volumes, and multiplicity of colon polyps in each group were evaluated. The microvessel density (MVD), the expressions of Proliferating Cell Nuclear Antigen (PCNA), and the expressions of HIF-1 α and VEGF in polyps were detected in each group. Results. Estrogen reduced the multiplicity, volumes, and the PCNA expressions of DMH-induced colon polyps. The MVD in DMH + E 2 group was significantly lower than that in DMH group. Estrogen treatment decreased the HIF-1 α and VEGF expressions at both mRNA and protein level. Conclusion. Estrogen replacement was protective for ovariectomized rats from DMH-induced carcinogenesis, and one of the mechanisms for this was due to estrogen’s inhibitive effects on blood vessel formation by downregulating VEGF and HIF-1 α expressions." @default.
• W2157426972 created "2016-06-24" @default.
• W2157426972 creator A5006295034 @default.
• W2157426972 creator A5043871243 @default.
• W2157426972 creator A5055751859 @default.
• W2157426972 creator A5068922710 @default.
• W2157426972 creator A5079375938 @default.
• W2157426972 creator A5088580824 @default.
• W2157426972 creator A5090815103 @default.
• W2157426972 date "2013-01-01" @default.
• W2157426972 modified "2023-10-16" @default.
• W2157426972 title "Estrogen Inhibits Colon Polyp Formation by Reducing Angiogenesis in a Carcinogen-Induced Rat Model" @default.
• W2157426972 cites W1976783896 @default.
• W2157426972 cites W1976888003 @default.
• W2157426972 cites W1979858258 @default.
• W2157426972 cites W1989935331 @default.
• W2157426972 cites W1995802267 @default.
• W2157426972 cites W2006273833 @default.
• W2157426972 cites W2033238275 @default.
• W2157426972 cites W2054956616 @default.
• W2157426972 cites W2058920288 @default.
• W2157426972 cites W2077129920 @default.
• W2157426972 cites W2085386332 @default.
• W2157426972 cites W2104285531 @default.
• W2157426972 cites W2109786560 @default.
• W2157426972 cites W2127654933 @default.
• W2157426972 cites W2128527557 @default.
• W2157426972 cites W2131826541 @default.
• W2157426972 cites W2144026946 @default.
• W2157426972 cites W2151528680 @default.
• W2157426972 cites W2152785381 @default.
• W2157426972 cites W2164414963 @default.
• W2157426972 cites W2312296163 @default.
• W2157426972 cites W2319962899 @default.
• W2157426972 cites W4230899916 @default.
• W2157426972 doi "https://doi.org/10.1155/2013/453898" @default.
• W2157426972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3848267" @default.
• W2157426972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24348555" @default.
• W2157426972 hasPublicationYear "2013" @default.
• W2157426972 type Work @default.
• W2157426972 sameAs 2157426972 @default.
• W2157426972 citedByCount "11" @default.
• W2157426972 countsByYear W21574269722016 @default.
• W2157426972 countsByYear W21574269722018 @default.
• W2157426972 countsByYear W21574269722019 @default.
• W2157426972 countsByYear W21574269722020 @default.
• W2157426972 countsByYear W21574269722022 @default.
• W2157426972 countsByYear W21574269722023 @default.
• W2157426972 crossrefType "journal-article" @default.
• W2157426972 hasAuthorship W2157426972A5006295034 @default.
• W2157426972 hasAuthorship W2157426972A5043871243 @default.
• W2157426972 hasAuthorship W2157426972A5055751859 @default.
• W2157426972 hasAuthorship W2157426972A5068922710 @default.
• W2157426972 hasAuthorship W2157426972A5079375938 @default.
• W2157426972 hasAuthorship W2157426972A5088580824 @default.
• W2157426972 hasAuthorship W2157426972A5090815103 @default.
• W2157426972 hasBestOaLocation W21574269721 @default.
• W2157426972 hasConcept C114246631 @default.
• W2157426972 hasConcept C121608353 @default.
• W2157426972 hasConcept C126322002 @default.
• W2157426972 hasConcept C134018914 @default.
• W2157426972 hasConcept C185592680 @default.
• W2157426972 hasConcept C204232928 @default.
• W2157426972 hasConcept C2777164284 @default.
• W2157426972 hasConcept C2778271429 @default.
• W2157426972 hasConcept C2780394083 @default.
• W2157426972 hasConcept C34688535 @default.
• W2157426972 hasConcept C526805850 @default.
• W2157426972 hasConcept C55493867 @default.
• W2157426972 hasConcept C555283112 @default.
• W2157426972 hasConcept C71924100 @default.
• W2157426972 hasConcept C8264082 @default.
• W2157426972 hasConceptScore W2157426972C114246631 @default.
• W2157426972 hasConceptScore W2157426972C121608353 @default.
• W2157426972 hasConceptScore W2157426972C126322002 @default.
• W2157426972 hasConceptScore W2157426972C134018914 @default.
• W2157426972 hasConceptScore W2157426972C185592680 @default.
• W2157426972 hasConceptScore W2157426972C204232928 @default.
• W2157426972 hasConceptScore W2157426972C2777164284 @default.
• W2157426972 hasConceptScore W2157426972C2778271429 @default.
• W2157426972 hasConceptScore W2157426972C2780394083 @default.
• W2157426972 hasConceptScore W2157426972C34688535 @default.
• W2157426972 hasConceptScore W2157426972C526805850 @default.
• W2157426972 hasConceptScore W2157426972C55493867 @default.
• W2157426972 hasConceptScore W2157426972C555283112 @default.
• W2157426972 hasConceptScore W2157426972C71924100 @default.
• W2157426972 hasConceptScore W2157426972C8264082 @default.
• W2157426972 hasFunder F4320321001 @default.
• W2157426972 hasLocation W21574269721 @default.
• W2157426972 hasLocation W21574269722 @default.
• W2157426972 hasLocation W21574269723 @default.
• W2157426972 hasLocation W21574269724 @default.
• W2157426972 hasLocation W21574269725 @default.
• W2157426972 hasOpenAccess W2157426972 @default.
• W2157426972 hasPrimaryLocation W21574269721 @default.
• W2157426972 hasRelatedWork W2047473481 @default.
• W2157426972 hasRelatedWork W2070612534 @default.
• W2157426972 hasRelatedWork W2075942210 @default.

• next