Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157450061> ?p ?o ?g. }
- W2157450061 endingPage "252" @default.
- W2157450061 startingPage "241" @default.
- W2157450061 abstract "Metabotropic glutamate receptors (mGluRs) mediate the effects of glutamate neurotransmission on intracellular second messenger systems. Among the seven distinct mGluR receptor isoforms currently identified, the mGluR5 isoform is expressed particularly prominently in the striatum, where it may contribute to neuronal plasticity, motor behaviors, and excitotoxic injury. mGluR5 mRNA expression in striatal enkephalinergic, somatostatinergic, and cholinergic neurons was examined using double label in situ hybridization techniques. mGluR5 expression is abundant in a large number of medium-sized striatal cells but is absent in a significant minority of neurons. Double label in situ hybridization with 35S-dATP- and digoxygenin-dUTP-tailed oligonucleotide probes demonstrated that mGluR5 message is highly expressed by enkephalinergic striatal neurons but is not detectable in cholinergic or somatostatin interneurons. In addition, some nonenkephalin, presumably substance P, neurons were also strongly labeled for mGluR5. The differential expression of mGluR5 in striatal projection neurons vs. interneurons may contribute to the selective vulnerability of these neurons to disease processes." @default.
- W2157450061 created "2016-06-24" @default.
- W2157450061 creator A5000374325 @default.
- W2157450061 creator A5010924149 @default.
- W2157450061 creator A5021070522 @default.
- W2157450061 creator A5027102645 @default.
- W2157450061 creator A5050751733 @default.
- W2157450061 date "1995-04-03" @default.
- W2157450061 modified "2023-10-11" @default.
- W2157450061 title "Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons" @default.
- W2157450061 cites W134400921 @default.
- W2157450061 cites W1503789839 @default.
- W2157450061 cites W1529166175 @default.
- W2157450061 cites W1542861050 @default.
- W2157450061 cites W1543271211 @default.
- W2157450061 cites W1564717701 @default.
- W2157450061 cites W1581931619 @default.
- W2157450061 cites W1594972985 @default.
- W2157450061 cites W1596012657 @default.
- W2157450061 cites W1615495952 @default.
- W2157450061 cites W1776364276 @default.
- W2157450061 cites W1857277871 @default.
- W2157450061 cites W1948270772 @default.
- W2157450061 cites W1964060360 @default.
- W2157450061 cites W1968616820 @default.
- W2157450061 cites W1970953072 @default.
- W2157450061 cites W1972183007 @default.
- W2157450061 cites W1975575774 @default.
- W2157450061 cites W1975814998 @default.
- W2157450061 cites W1978572562 @default.
- W2157450061 cites W1980435560 @default.
- W2157450061 cites W1985420205 @default.
- W2157450061 cites W1987434382 @default.
- W2157450061 cites W1991206010 @default.
- W2157450061 cites W1991603311 @default.
- W2157450061 cites W1993068285 @default.
- W2157450061 cites W1996570128 @default.
- W2157450061 cites W2001600462 @default.
- W2157450061 cites W2003179182 @default.
- W2157450061 cites W2004543262 @default.
- W2157450061 cites W2004930085 @default.
- W2157450061 cites W2007239691 @default.
- W2157450061 cites W2008531141 @default.
- W2157450061 cites W2009077347 @default.
- W2157450061 cites W2013063789 @default.
- W2157450061 cites W2020352440 @default.
- W2157450061 cites W2021540475 @default.
- W2157450061 cites W2024042286 @default.
- W2157450061 cites W2025170140 @default.
- W2157450061 cites W2027998184 @default.
- W2157450061 cites W2028627863 @default.
- W2157450061 cites W2030903240 @default.
- W2157450061 cites W2033188783 @default.
- W2157450061 cites W2034906758 @default.
- W2157450061 cites W2035814278 @default.
- W2157450061 cites W2042714196 @default.
- W2157450061 cites W2044310015 @default.
- W2157450061 cites W2045490270 @default.
- W2157450061 cites W2045628566 @default.
- W2157450061 cites W2046111418 @default.
- W2157450061 cites W2050579962 @default.
- W2157450061 cites W2050867708 @default.
- W2157450061 cites W2051293971 @default.
- W2157450061 cites W2055043387 @default.
- W2157450061 cites W2062637879 @default.
- W2157450061 cites W2063185527 @default.
- W2157450061 cites W2066439205 @default.
- W2157450061 cites W2070027885 @default.
- W2157450061 cites W2073561633 @default.
- W2157450061 cites W2074040480 @default.
- W2157450061 cites W2074307342 @default.
- W2157450061 cites W2074402500 @default.
- W2157450061 cites W2075316492 @default.
- W2157450061 cites W2078191693 @default.
- W2157450061 cites W2080120821 @default.
- W2157450061 cites W2081234982 @default.
- W2157450061 cites W2082556611 @default.
- W2157450061 cites W2090121173 @default.
- W2157450061 cites W2095545913 @default.
- W2157450061 cites W2101116630 @default.
- W2157450061 cites W2117593813 @default.
- W2157450061 cites W2129112055 @default.
- W2157450061 cites W2136306454 @default.
- W2157450061 cites W2140142911 @default.
- W2157450061 cites W2142788418 @default.
- W2157450061 cites W2147428924 @default.
- W2157450061 cites W2149201522 @default.
- W2157450061 cites W2161584310 @default.
- W2157450061 cites W2174668858 @default.
- W2157450061 cites W2266315341 @default.
- W2157450061 cites W2341695286 @default.
- W2157450061 cites W2472577924 @default.
- W2157450061 cites W2489024985 @default.
- W2157450061 doi "https://doi.org/10.1002/cne.903540207" @default.
- W2157450061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7782501" @default.
- W2157450061 hasPublicationYear "1995" @default.
- W2157450061 type Work @default.
- W2157450061 sameAs 2157450061 @default.