Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157528422> ?p ?o ?g. }
- W2157528422 endingPage "83" @default.
- W2157528422 startingPage "74" @default.
- W2157528422 abstract "Intensive glycemic control can reduce the risk of microvascular complications in patients with type 2 diabetes mellitus (T2DM). However, hypoglycemia induced by diabetes medications is recognized as a major limiting factor in the attainment of glycemic goals. Mild hypoglycemia is relatively common in patients with T2DM, and the prevalence of severe hypoglycemia increases with insulin treatment and can approach the prevalence seen in patients with type 1 diabetes. Mild hypoglycemia and the fear of hypoglycemia can have a substantial impact on the physical, mental, social, and economic well–being of patients with T2DM. Severe hypoglycemia is more serious and may be associated with an increased risk of dementia, cardiovascular events, and death. Insulin and insulin secretagogue therapies (eg, sulfonylureas and meglitinides) are the major causes of hypoglycemia in patients with T2DM. Other diabetes drugs, such as metformin, when used as monotherapy, have a low risk of hypoglycemia. Emerging experimental therapies, such as activators of the free fatty acid receptor 1, G protein–coupled receptor 119 agonists, glucokinase activators, inhibitors of 11β-hydroxysteroid dehydrogenase type 1, and sodium–glucose co–transporter 2 inhibitors, some of which have mechanisms of action consistent with a potential low risk of hypoglycemia, may help patients with T2DM achieve improved glycemic control." @default.
- W2157528422 created "2016-06-24" @default.
- W2157528422 creator A5062486589 @default.
- W2157528422 date "2012-07-01" @default.
- W2157528422 modified "2023-09-25" @default.
- W2157528422 title "Hypoglycemic Potential of Current and Emerging Pharmacotherapies in Type 2 Diabetes Mellitus" @default.
- W2157528422 cites W1518589347 @default.
- W2157528422 cites W1953840628 @default.
- W2157528422 cites W1963557257 @default.
- W2157528422 cites W1973240292 @default.
- W2157528422 cites W1974115114 @default.
- W2157528422 cites W1993323173 @default.
- W2157528422 cites W2007003907 @default.
- W2157528422 cites W2008443217 @default.
- W2157528422 cites W2013481385 @default.
- W2157528422 cites W2014554878 @default.
- W2157528422 cites W2015409124 @default.
- W2157528422 cites W2016400372 @default.
- W2157528422 cites W2021446295 @default.
- W2157528422 cites W2024529821 @default.
- W2157528422 cites W2028192858 @default.
- W2157528422 cites W2045923887 @default.
- W2157528422 cites W2046188044 @default.
- W2157528422 cites W2048930008 @default.
- W2157528422 cites W2057651652 @default.
- W2157528422 cites W2060911425 @default.
- W2157528422 cites W2069150029 @default.
- W2157528422 cites W2076573528 @default.
- W2157528422 cites W2081510795 @default.
- W2157528422 cites W2084511068 @default.
- W2157528422 cites W2086595398 @default.
- W2157528422 cites W2087036494 @default.
- W2157528422 cites W2091582775 @default.
- W2157528422 cites W2096329362 @default.
- W2157528422 cites W2097995302 @default.
- W2157528422 cites W2098289172 @default.
- W2157528422 cites W2100442612 @default.
- W2157528422 cites W2107222124 @default.
- W2157528422 cites W2107648636 @default.
- W2157528422 cites W2108646121 @default.
- W2157528422 cites W2109093140 @default.
- W2157528422 cites W2111047373 @default.
- W2157528422 cites W2111181130 @default.
- W2157528422 cites W2113550312 @default.
- W2157528422 cites W2114076019 @default.
- W2157528422 cites W2114276479 @default.
- W2157528422 cites W2120472804 @default.
- W2157528422 cites W2122077393 @default.
- W2157528422 cites W2123946565 @default.
- W2157528422 cites W2123984464 @default.
- W2157528422 cites W2132041174 @default.
- W2157528422 cites W2143910895 @default.
- W2157528422 cites W2146116274 @default.
- W2157528422 cites W2146901298 @default.
- W2157528422 cites W2156597872 @default.
- W2157528422 cites W2156888511 @default.
- W2157528422 cites W2158573360 @default.
- W2157528422 cites W2160157473 @default.
- W2157528422 cites W2162576174 @default.
- W2157528422 cites W2163448046 @default.
- W2157528422 cites W2165449026 @default.
- W2157528422 cites W2167245776 @default.
- W2157528422 cites W2171786511 @default.
- W2157528422 cites W2172193326 @default.
- W2157528422 cites W2188846692 @default.
- W2157528422 cites W2337454357 @default.
- W2157528422 cites W4210970044 @default.
- W2157528422 cites W4236895722 @default.
- W2157528422 cites W4250647894 @default.
- W2157528422 cites W4253271202 @default.
- W2157528422 doi "https://doi.org/10.3810/pgm.2012.07.2570" @default.
- W2157528422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22913896" @default.
- W2157528422 hasPublicationYear "2012" @default.
- W2157528422 type Work @default.
- W2157528422 sameAs 2157528422 @default.
- W2157528422 citedByCount "14" @default.
- W2157528422 countsByYear W21575284222013 @default.
- W2157528422 countsByYear W21575284222014 @default.
- W2157528422 countsByYear W21575284222015 @default.
- W2157528422 countsByYear W21575284222016 @default.
- W2157528422 countsByYear W21575284222018 @default.
- W2157528422 countsByYear W21575284222020 @default.
- W2157528422 countsByYear W21575284222023 @default.
- W2157528422 crossrefType "journal-article" @default.
- W2157528422 hasAuthorship W2157528422A5062486589 @default.
- W2157528422 hasConcept C126322002 @default.
- W2157528422 hasConcept C134018914 @default.
- W2157528422 hasConcept C2777180221 @default.
- W2157528422 hasConcept C2779306644 @default.
- W2157528422 hasConcept C2780323712 @default.
- W2157528422 hasConcept C2780473172 @default.
- W2157528422 hasConcept C2780668416 @default.
- W2157528422 hasConcept C2910068830 @default.
- W2157528422 hasConcept C555293320 @default.
- W2157528422 hasConcept C71924100 @default.
- W2157528422 hasConceptScore W2157528422C126322002 @default.
- W2157528422 hasConceptScore W2157528422C134018914 @default.
- W2157528422 hasConceptScore W2157528422C2777180221 @default.