Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157553399> ?p ?o ?g. }
- W2157553399 endingPage "25" @default.
- W2157553399 startingPage "15" @default.
- W2157553399 abstract "One of the functions of the immune system is to recognize and destroy abnormal or infected cells to maintain homeostasis. This is accomplished by cytotoxic lymphocytes. Cytotoxicity is a highly organized multifactor process. Here, we reviewed the apoptosis pathways induced by the two main cytotoxic lymphocyte subsets, natural killer (NK) cells and CD8+ T cells. In base to recent experimental evidence, we reviewed NK receptors involved in recognition of target-cell, as well as lytic molecules such as perforin, granzymes-A and -B, and granulysin. In addition, we reviewed the Fas-FasL intercellular linkage mediated pathway, and briefly the cross-linking of tumor necrosis factor (TNF) and TNF receptor pathway. We discussed three models of possible molecular interaction between lytic molecules from effector cytotoxic cells and target-cell membrane to induction of apoptosis." @default.
- W2157553399 created "2016-06-24" @default.
- W2157553399 creator A5005762549 @default.
- W2157553399 creator A5019844134 @default.
- W2157553399 creator A5046350479 @default.
- W2157553399 creator A5073479455 @default.
- W2157553399 creator A5077105494 @default.
- W2157553399 date "2009-02-01" @default.
- W2157553399 modified "2023-09-30" @default.
- W2157553399 title "Cell Death Mechanisms Induced by Cytotoxic Lymphocytes" @default.
- W2157553399 cites W1516581843 @default.
- W2157553399 cites W1532325696 @default.
- W2157553399 cites W1539591812 @default.
- W2157553399 cites W1903544242 @default.
- W2157553399 cites W1951959278 @default.
- W2157553399 cites W1964617786 @default.
- W2157553399 cites W1970563382 @default.
- W2157553399 cites W1974351164 @default.
- W2157553399 cites W1975155851 @default.
- W2157553399 cites W1982051091 @default.
- W2157553399 cites W1997196319 @default.
- W2157553399 cites W2002503549 @default.
- W2157553399 cites W2006027051 @default.
- W2157553399 cites W2015015493 @default.
- W2157553399 cites W2016914965 @default.
- W2157553399 cites W2017072222 @default.
- W2157553399 cites W2021820438 @default.
- W2157553399 cites W2028091596 @default.
- W2157553399 cites W2066300320 @default.
- W2157553399 cites W2070509529 @default.
- W2157553399 cites W2076317085 @default.
- W2157553399 cites W2086899319 @default.
- W2157553399 cites W2097937083 @default.
- W2157553399 cites W2116570389 @default.
- W2157553399 cites W2136706405 @default.
- W2157553399 cites W2142285575 @default.
- W2157553399 cites W2164514428 @default.
- W2157553399 cites W2170523250 @default.
- W2157553399 doi "https://doi.org/10.1038/cmi.2009.3" @default.
- W2157553399 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4002546" @default.
- W2157553399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19254476" @default.
- W2157553399 hasPublicationYear "2009" @default.
- W2157553399 type Work @default.
- W2157553399 sameAs 2157553399 @default.
- W2157553399 citedByCount "273" @default.
- W2157553399 countsByYear W21575533992012 @default.
- W2157553399 countsByYear W21575533992013 @default.
- W2157553399 countsByYear W21575533992014 @default.
- W2157553399 countsByYear W21575533992015 @default.
- W2157553399 countsByYear W21575533992016 @default.
- W2157553399 countsByYear W21575533992017 @default.
- W2157553399 countsByYear W21575533992018 @default.
- W2157553399 countsByYear W21575533992019 @default.
- W2157553399 countsByYear W21575533992020 @default.
- W2157553399 countsByYear W21575533992021 @default.
- W2157553399 countsByYear W21575533992022 @default.
- W2157553399 countsByYear W21575533992023 @default.
- W2157553399 crossrefType "journal-article" @default.
- W2157553399 hasAuthorship W2157553399A5005762549 @default.
- W2157553399 hasAuthorship W2157553399A5019844134 @default.
- W2157553399 hasAuthorship W2157553399A5046350479 @default.
- W2157553399 hasAuthorship W2157553399A5073479455 @default.
- W2157553399 hasAuthorship W2157553399A5077105494 @default.
- W2157553399 hasBestOaLocation W21575533992 @default.
- W2157553399 hasConcept C109316439 @default.
- W2157553399 hasConcept C129374314 @default.
- W2157553399 hasConcept C154317977 @default.
- W2157553399 hasConcept C167672396 @default.
- W2157553399 hasConcept C182615771 @default.
- W2157553399 hasConcept C183193105 @default.
- W2157553399 hasConcept C190283241 @default.
- W2157553399 hasConcept C19317047 @default.
- W2157553399 hasConcept C202751555 @default.
- W2157553399 hasConcept C203014093 @default.
- W2157553399 hasConcept C2522874641 @default.
- W2157553399 hasConcept C2776062744 @default.
- W2157553399 hasConcept C2776090121 @default.
- W2157553399 hasConcept C2777966294 @default.
- W2157553399 hasConcept C2778102761 @default.
- W2157553399 hasConcept C28651165 @default.
- W2157553399 hasConcept C31573885 @default.
- W2157553399 hasConcept C51785407 @default.
- W2157553399 hasConcept C55493867 @default.
- W2157553399 hasConcept C66008609 @default.
- W2157553399 hasConcept C86803240 @default.
- W2157553399 hasConcept C8891405 @default.
- W2157553399 hasConcept C95444343 @default.
- W2157553399 hasConcept C9756297 @default.
- W2157553399 hasConceptScore W2157553399C109316439 @default.
- W2157553399 hasConceptScore W2157553399C129374314 @default.
- W2157553399 hasConceptScore W2157553399C154317977 @default.
- W2157553399 hasConceptScore W2157553399C167672396 @default.
- W2157553399 hasConceptScore W2157553399C182615771 @default.
- W2157553399 hasConceptScore W2157553399C183193105 @default.
- W2157553399 hasConceptScore W2157553399C190283241 @default.
- W2157553399 hasConceptScore W2157553399C19317047 @default.
- W2157553399 hasConceptScore W2157553399C202751555 @default.
- W2157553399 hasConceptScore W2157553399C203014093 @default.