Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157783283> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2157783283 endingPage "1045" @default.
- W2157783283 startingPage "1045" @default.
- W2157783283 abstract "<h3>Background</h3> Trimethoprim therapy can cause hyperkalemia and is often coprescribed with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs). The objective of this study was to characterize the risk of hyperkalemia-associated hospitalization in elderly patients who were being treated with trimethoprim-sulfamethoxazole along with either an ACEI or an ARB. <h3>Methods</h3> We conducted a population-based, nested case-control study of a cohort of elderly patients 66 years or older who were residents of Ontario, Canada, and who were receiving continuous therapy with either an ACEI or an ARB. Case patients were those with a hyperkalemia-associated hospitalization within 14 days of receiving a prescription for trimethoprim-sulfamethoxazole, amoxicillin, ciprofloxacin, norfloxacin, or nitrofurantoin. For each case, we identified up to 4 control patients from the same cohort matched for age, sex, and presence or absence of chronic renal disease and diabetes. Odds ratios were determined for the association between hyperkalemia-associated hospitalization and previous antibiotic use. <h3>Results</h3> During the 14-year study period, we identified 4148 admissions involving hyperkalemia, 371 of which occurred within 14 days of antibiotic exposure. Compared with amoxicillin, the use of trimethoprim-sulfamethoxazole was associated with a nearly 7-fold increased risk of hyperkalemia-associated hospitalization (adjusted odds ratio, 6.7; 95% confidence interval, 4.5-10.0). No such risk was found with the use of comparator antibiotics. <h3>Conclusions</h3> Among older patients treated with ACEIs or ARBs, the use of trimethoprim-sulfamethoxazole is associated with a major increase in the risk of hyperkalemia-associated hospitalization relative to other antibiotics. Alternate antibiotic therapy should be considered in these patients when clinically appropriate." @default.
- W2157783283 created "2016-06-24" @default.
- W2157783283 creator A5054833763 @default.
- W2157783283 date "2010-06-28" @default.
- W2157783283 modified "2023-10-03" @default.
- W2157783283 title "Trimethoprim-Sulfamethoxazole–Induced Hyperkalemia in Patients Receiving Inhibitors of the Renin-Angiotensin System" @default.
- W2157783283 cites W180946569 @default.
- W2157783283 cites W1973245422 @default.
- W2157783283 cites W1984205491 @default.
- W2157783283 cites W1991106789 @default.
- W2157783283 cites W2000445173 @default.
- W2157783283 cites W2005685615 @default.
- W2157783283 cites W2015959379 @default.
- W2157783283 cites W2038012076 @default.
- W2157783283 cites W2047741379 @default.
- W2157783283 cites W2059217331 @default.
- W2157783283 cites W2061075125 @default.
- W2157783283 cites W2062975680 @default.
- W2157783283 cites W2065975091 @default.
- W2157783283 cites W2074341912 @default.
- W2157783283 cites W2074976399 @default.
- W2157783283 cites W2078197568 @default.
- W2157783283 cites W2079048795 @default.
- W2157783283 cites W2090034411 @default.
- W2157783283 cites W2093767567 @default.
- W2157783283 cites W2111945961 @default.
- W2157783283 cites W2147804563 @default.
- W2157783283 cites W2152798629 @default.
- W2157783283 cites W2164498941 @default.
- W2157783283 doi "https://doi.org/10.1001/archinternmed.2010.142" @default.
- W2157783283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20585070" @default.
- W2157783283 hasPublicationYear "2010" @default.
- W2157783283 type Work @default.
- W2157783283 sameAs 2157783283 @default.
- W2157783283 citedByCount "102" @default.
- W2157783283 countsByYear W21577832832012 @default.
- W2157783283 countsByYear W21577832832013 @default.
- W2157783283 countsByYear W21577832832014 @default.
- W2157783283 countsByYear W21577832832015 @default.
- W2157783283 countsByYear W21577832832016 @default.
- W2157783283 countsByYear W21577832832017 @default.
- W2157783283 countsByYear W21577832832018 @default.
- W2157783283 countsByYear W21577832832019 @default.
- W2157783283 countsByYear W21577832832020 @default.
- W2157783283 countsByYear W21577832832021 @default.
- W2157783283 countsByYear W21577832832022 @default.
- W2157783283 countsByYear W21577832832023 @default.
- W2157783283 crossrefType "journal-article" @default.
- W2157783283 hasAuthorship W2157783283A5054833763 @default.
- W2157783283 hasConcept C126322002 @default.
- W2157783283 hasConcept C156957248 @default.
- W2157783283 hasConcept C2779425571 @default.
- W2157783283 hasConcept C2780243291 @default.
- W2157783283 hasConcept C2780728791 @default.
- W2157783283 hasConcept C2908647359 @default.
- W2157783283 hasConcept C501593827 @default.
- W2157783283 hasConcept C71924100 @default.
- W2157783283 hasConcept C72563966 @default.
- W2157783283 hasConcept C86803240 @default.
- W2157783283 hasConcept C89423630 @default.
- W2157783283 hasConcept C99454951 @default.
- W2157783283 hasConceptScore W2157783283C126322002 @default.
- W2157783283 hasConceptScore W2157783283C156957248 @default.
- W2157783283 hasConceptScore W2157783283C2779425571 @default.
- W2157783283 hasConceptScore W2157783283C2780243291 @default.
- W2157783283 hasConceptScore W2157783283C2780728791 @default.
- W2157783283 hasConceptScore W2157783283C2908647359 @default.
- W2157783283 hasConceptScore W2157783283C501593827 @default.
- W2157783283 hasConceptScore W2157783283C71924100 @default.
- W2157783283 hasConceptScore W2157783283C72563966 @default.
- W2157783283 hasConceptScore W2157783283C86803240 @default.
- W2157783283 hasConceptScore W2157783283C89423630 @default.
- W2157783283 hasConceptScore W2157783283C99454951 @default.
- W2157783283 hasIssue "12" @default.
- W2157783283 hasLocation W21577832831 @default.
- W2157783283 hasLocation W21577832832 @default.
- W2157783283 hasOpenAccess W2157783283 @default.
- W2157783283 hasPrimaryLocation W21577832831 @default.
- W2157783283 hasRelatedWork W2016793986 @default.
- W2157783283 hasRelatedWork W2328000393 @default.
- W2157783283 hasRelatedWork W2409120838 @default.
- W2157783283 hasRelatedWork W2409153138 @default.
- W2157783283 hasRelatedWork W2460618973 @default.
- W2157783283 hasRelatedWork W4239075073 @default.
- W2157783283 hasRelatedWork W4245745103 @default.
- W2157783283 hasRelatedWork W4377084086 @default.
- W2157783283 hasRelatedWork W4381162782 @default.
- W2157783283 hasRelatedWork W2943043725 @default.
- W2157783283 hasVolume "170" @default.
- W2157783283 isParatext "false" @default.
- W2157783283 isRetracted "false" @default.
- W2157783283 magId "2157783283" @default.
- W2157783283 workType "article" @default.