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• W2157797876 abstract "To evaluate the utility of serum biomarkers in the diagnosis of preeclampsia (PE) and also investigate possible correlation with pathogenesis of PE.Maternal serum concentrations of heme oxygenase-1 (HO1) and N-myc downstream-regulated gene 1 (NDRG1) were measured at 27-34 weeks of gestation in a case-control study of 33 pregnant women diagnosed with PE and in 43 normotensive pregnant women without proteinuria. The Mann-Whitney U test and Spearman's correlation were used for statistical analysis.The median serum HO1 level was found to be significantly higher in the PE group [76.7 ng/ml (23.4-445.7)] than control group [55.9 ng/ml (3.7-354.3)] (p = 0.006). Positive correlation was found between HO1 levels with presence of PE (r = 0.316, p = 0.005). There was no significant difference in NDRG1 values between the two groups (p = 0.226).Serum HO1 levels were found to be increased in patients with PE compared with normotensive pregnant women." @default.
• W2157797876 created "2016-06-24" @default.
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• W2157797876 date "2014-08-11" @default.
• W2157797876 modified "2023-10-03" @default.
• W2157797876 title "Increased serum heme oxygenase-1 levels as a diagnostic marker of oxidative stress in preeclampsia" @default.
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• W2157797876 doi "https://doi.org/10.3109/10641955.2014.946613" @default.
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