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- W2157801969 abstract "The study of evolutionary processes is necessarily retrospective, but past pathways can lull us into imagining that future changes will generally follow the same trajectory. The arms races between pathogens and drugs provide a particularly useful window to view these events in relatively short time frames. In PNAS, Pelleau et al. (1) provide an excellent demonstration of these selective changes. Their paper details an unexpected mechanism by which Plasmodium falciparum malaria parasites responded to the pressure of antimalarial medicines in French Guiana. Their analysis combines long-term surveillance of the parasites in the field with genomic analysis and precise editing of the gene involved to demonstrate interesting twists that organisms use to evade existential threats." @default.
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- W2157801969 date "2015-09-02" @default.
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- W2157801969 title "Fusion of field studies and the laboratory solves a puzzle in antimalarial resistance" @default.
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- W2157801969 doi "https://doi.org/10.1073/pnas.1514403112" @default.
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