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• W2157805655 startingPage "2553" @default.
• W2157805655 abstract "In Saccharomyces cerevisiae the pyruvate dehydrogenase (PDH) complex is regulated by reversible phosphorylation of its Pda1p subunit. We here provide evidence that Pda1p is phosphorylated by the mitochondrial kinase Yil042cp. Deletion of YOR090c, encoding a putative mitochondrial phosphatase, results in a decreased PDH activity, indicating that Yor090cp acts as the corresponding PDH phosphatase. We demonstrate by means of blue native gel electrophoresis and tandem affinity purification that both enzymes are associated with the PDH complex." @default.
• W2157805655 created "2016-06-24" @default.
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• W2157805655 date "2006-04-12" @default.
• W2157805655 modified "2023-10-14" @default.
• W2157805655 title "<i>YIL042c</i>and<i>YOR090c</i>encode the kinase and phosphatase of the<i>Saccharomyces cerevisiae</i>pyruvate dehydrogenase complex" @default.
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• W2157805655 doi "https://doi.org/10.1016/j.febslet.2006.04.002" @default.
• W2157805655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16643908" @default.
• W2157805655 hasPublicationYear "2006" @default.
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