FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157820340> ?p ?o ?g. }

• W2157820340 abstract "Abstract Background Activities of drug molecules can be predicted by QSAR (quantitative structure activity relationship) models, which overcomes the disadvantages of high cost and long cycle by employing the traditional experimental method. With the fact that the number of drug molecules with positive activity is rather fewer than that of negatives, it is important to predict molecular activities considering such an unbalanced situation. Results Here, asymmetric bagging and feature selection are introduced into the problem and asymmetric bagging of support vector machines (asBagging) is proposed on predicting drug activities to treat the unbalanced problem. At the same time, the features extracted from the structures of drug molecules affect prediction accuracy of QSAR models. Therefore, a novel algorithm named PRIFEAB is proposed, which applies an embedded feature selection method to remove redundant and irrelevant features for asBagging. Numerical experimental results on a data set of molecular activities show that asBagging improve the AUC and sensitivity values of molecular activities and PRIFEAB with feature selection further helps to improve the prediction ability. Conclusion Asymmetric bagging can help to improve prediction accuracy of activities of drug molecules, which can be furthermore improved by performing feature selection to select relevant features from the drug molecules data sets." @default.
• W2157820340 created "2016-06-24" @default.
• W2157820340 creator A5037410384 @default.
• W2157820340 creator A5049619483 @default.
• W2157820340 creator A5083054357 @default.
• W2157820340 creator A5087539432 @default.
• W2157820340 creator A5089711319 @default.
• W2157820340 date "2008-05-01" @default.
• W2157820340 modified "2023-10-18" @default.
• W2157820340 title "Asymmetric bagging and feature selection for activities prediction of drug molecules" @default.
• W2157820340 cites W1545231783 @default.
• W2157820340 cites W1819658147 @default.
• W2157820340 cites W1967405986 @default.
• W2157820340 cites W1971327393 @default.
• W2157820340 cites W1984639110 @default.
• W2157820340 cites W1990152497 @default.
• W2157820340 cites W1991537916 @default.
• W2157820340 cites W2001597746 @default.
• W2157820340 cites W2007436490 @default.
• W2157820340 cites W2014158063 @default.
• W2157820340 cites W2017337590 @default.
• W2157820340 cites W2021651928 @default.
• W2157820340 cites W2028749140 @default.
• W2157820340 cites W2034038739 @default.
• W2157820340 cites W2049334526 @default.
• W2157820340 cites W2087347434 @default.
• W2157820340 cites W2131782167 @default.
• W2157820340 cites W2138516811 @default.
• W2157820340 cites W2143426320 @default.
• W2157820340 cites W2148804536 @default.
• W2157820340 cites W2152761983 @default.
• W2157820340 cites W2156717157 @default.
• W2157820340 cites W2204819850 @default.
• W2157820340 cites W2205415869 @default.
• W2157820340 cites W4302609338 @default.
• W2157820340 doi "https://doi.org/10.1186/1471-2105-9-s6-s7" @default.
• W2157820340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2423448" @default.
• W2157820340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18541060" @default.
• W2157820340 hasPublicationYear "2008" @default.
• W2157820340 type Work @default.
• W2157820340 sameAs 2157820340 @default.
• W2157820340 citedByCount "36" @default.
• W2157820340 countsByYear W21578203402012 @default.
• W2157820340 countsByYear W21578203402013 @default.
• W2157820340 countsByYear W21578203402014 @default.
• W2157820340 countsByYear W21578203402015 @default.
• W2157820340 countsByYear W21578203402017 @default.
• W2157820340 countsByYear W21578203402019 @default.
• W2157820340 countsByYear W21578203402020 @default.
• W2157820340 countsByYear W21578203402021 @default.
• W2157820340 countsByYear W21578203402022 @default.
• W2157820340 countsByYear W21578203402023 @default.
• W2157820340 crossrefType "journal-article" @default.
• W2157820340 hasAuthorship W2157820340A5037410384 @default.
• W2157820340 hasAuthorship W2157820340A5049619483 @default.
• W2157820340 hasAuthorship W2157820340A5083054357 @default.
• W2157820340 hasAuthorship W2157820340A5087539432 @default.
• W2157820340 hasAuthorship W2157820340A5089711319 @default.
• W2157820340 hasBestOaLocation W21578203401 @default.
• W2157820340 hasConcept C119857082 @default.
• W2157820340 hasConcept C12267149 @default.
• W2157820340 hasConcept C124101348 @default.
• W2157820340 hasConcept C138885662 @default.
• W2157820340 hasConcept C148483581 @default.
• W2157820340 hasConcept C153180895 @default.
• W2157820340 hasConcept C154945302 @default.
• W2157820340 hasConcept C164126121 @default.
• W2157820340 hasConcept C164923092 @default.
• W2157820340 hasConcept C177264268 @default.
• W2157820340 hasConcept C199360897 @default.
• W2157820340 hasConcept C2776401178 @default.
• W2157820340 hasConcept C2780035454 @default.
• W2157820340 hasConcept C41008148 @default.
• W2157820340 hasConcept C41895202 @default.
• W2157820340 hasConcept C81917197 @default.
• W2157820340 hasConcept C86803240 @default.
• W2157820340 hasConcept C98274493 @default.
• W2157820340 hasConceptScore W2157820340C119857082 @default.
• W2157820340 hasConceptScore W2157820340C12267149 @default.
• W2157820340 hasConceptScore W2157820340C124101348 @default.
• W2157820340 hasConceptScore W2157820340C138885662 @default.
• W2157820340 hasConceptScore W2157820340C148483581 @default.
• W2157820340 hasConceptScore W2157820340C153180895 @default.
• W2157820340 hasConceptScore W2157820340C154945302 @default.
• W2157820340 hasConceptScore W2157820340C164126121 @default.
• W2157820340 hasConceptScore W2157820340C164923092 @default.
• W2157820340 hasConceptScore W2157820340C177264268 @default.
• W2157820340 hasConceptScore W2157820340C199360897 @default.
• W2157820340 hasConceptScore W2157820340C2776401178 @default.
• W2157820340 hasConceptScore W2157820340C2780035454 @default.
• W2157820340 hasConceptScore W2157820340C41008148 @default.
• W2157820340 hasConceptScore W2157820340C41895202 @default.
• W2157820340 hasConceptScore W2157820340C81917197 @default.
• W2157820340 hasConceptScore W2157820340C86803240 @default.
• W2157820340 hasConceptScore W2157820340C98274493 @default.
• W2157820340 hasIssue "S6" @default.
• W2157820340 hasLocation W21578203401 @default.
• W2157820340 hasLocation W21578203402 @default.
• W2157820340 hasLocation W21578203403 @default.
• W2157820340 hasLocation W21578203404 @default.

• next