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- W2157843460 abstract "One of the most reliable in vitro method to diagnose allergic sensitization is the qualitative determination Phadiatop®. We detected allergic sensitivity against a panel of common allergens present in the northwestern region of Mexico, in a preschool popullation, and also quantified tryptase and eosinophil cationic protein (ECP). Approved by the Ethics Committee. A total of sixty four children (ages 3-6 years) serum samples were analyzed by Phadiatop ® for determined specific IgE, and tryptasa and ECP by Phadia ImmunoCAP® 100. The group 1 included children sensitized (n = 10), and group 2, with non-sensitized children (n=54). All children studied were sensitive to pollens, specifically Artemis vulgaris, Fraxinus americana and Phleum pratense. Only 9 children were found specific IgE antibodies against Betula verrucosa. It was observed that seven children were sensitive to the cockroach (Periplaneta americana) and house dust. Additionally four children were sensitized to dog dander and three to house dust mites (Dermatophagoides pteronyssinus). Finally, in three children the analysis found specific IgE antibodies against cat dander and one positive to Alternaria alternata. In the determination of markers of inflammation, no significant differences were observed between the two groups, ECP values (p=0.062) and tryptase (p=0.518). This study is important because it teaches the importance of early detection of allergic sensitization by a positive Phadiatop ® test in still asymptomatic children or children with symptoms but no diagnosis and leads to take steps to avoid the allergic march." @default.
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- W2157843460 date "2014-02-01" @default.
- W2157843460 modified "2023-09-27" @default.
- W2157843460 title "Allergic Sensitization and Determination Of Serum Eosinophil Cationic Protein and Triptase In Preschool Population In Hermosillo, Sonora, Mexico" @default.
- W2157843460 doi "https://doi.org/10.1016/j.jaci.2013.12.343" @default.
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