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- W2157847511 abstract "Ultrastructure, molecular composition and electrophysiological properties of cardiac myocytes and functional characteristics of the fish heart suggest that cycling of extracellular Ca2+ is generally more important than intracellular cycling of Ca2+ stores of the sarcoplasmic reticulum (SR) in activating contraction of fish cardiac myocytes. This is especially true for the ventricle. However, prominent species-specific differences exist in cardiac excitation-contraction coupling and in the relative roles of extracellular and intracellular Ca2+ sources among the teleostean fish. In fact, in some fish species (tunas, burbot) the SR of atrial myocytes, under certain circumstances, may act as the major source of systolic Ca2+. These interspecific differences are obviously an outcome of evolutionary adaptation to different habitats and modes of activity in these habitats. There is also substantial intraspecific variation in the SR Ca2+-release-to-SL-Ca2+ influx ratio depending on acute and chronic temperature changes. Consequently excitation-contraction coupling of the fish cardiac myocytes is not a fixed entity, but rather a highly variable and malleable process that enables fish to have an appropriate cardiac scope to exploit a diverse range of environments." @default.
- W2157847511 created "2016-06-24" @default.
- W2157847511 creator A5062989015 @default.
- W2157847511 creator A5074400045 @default.
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- W2157847511 date "2002-08-01" @default.
- W2157847511 modified "2023-10-15" @default.
- W2157847511 title "Plasticity of excitation–contraction coupling in fish cardiac myocytes" @default.
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- W2157847511 doi "https://doi.org/10.1016/s1095-6433(02)00051-x" @default.
- W2157847511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12095866" @default.
- W2157847511 hasPublicationYear "2002" @default.
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