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• W2157944286 abstract "From the standpoint of diagnosis and treatment the epilepsies may be divided into two groups, symptomatic and cryptogenic. In many cases the cause is readily recognized or may be reasonably assumed (for example, brain tumor, posttraumatic scars of the cerebral cortex, eclampsia, or uremia). There remains, however,a considerable group in which no cause has yet been found. Many of these cases will fall into the clinical classification of “essential” or “idiopathic” epilepsy and may show a characteristic spike and slow-wave pattern on the electro-graphic tracing. It is this group that has been termed cryptogenic, meaning “of obscure origin.” In these cases the condition is usually familial. Classification of each case should be attempted on both an anatomical and an etiologic basis, in accordance with Tables I and II. The latter table is by no means complete but does list the common causes which must be kept in mind during the investigation of any case of epileptic seizures. In addition, the age of “the patient at the onset of the seizures will help focus attention on lesions of certain types. The commonest causes of habitual seizures beginning in infancy, for example, are birth injuries, degenerative lesions, and congenital abnormalities. Expanding Lesions Intracranial tumors of infancy and childhood do not often cause seizures because they are most often cerebellar in location. For seizures beginning between thirty-five and fifty-five years of age, however, neoplasms are the second commonest cause. Penfield, Erickson, and Tarlov (8) analyzed 703 verified cases of expanding intracranial lesions in relation to seizures, and their conclusions may be synopsized as follows. There were 149 infratentorial expanding lesions none of which produced epileptic seizures. Seizures in frontal, parietal and temporal lobe lesions were almost twice as common as in occipital lobe lesions. Lesions of the pituitary, thalamus, and basal ganglia produced seizures in only 8 per cent of cases. In a general way seizures become more common as the fissure of Rolando is approached. In a group of 230 verified gliomata occurring above the tentorium, the lowest incidence of seizures was among the most malignant lesions (glioblastoma multiforme, 37 per cent) and the highest incidence among the most slowly growing (oligodendroglioma, 92 per cent). Meningeal fibroblastomata produced seizures in 67 per cent of the cases studied. In the presence of a subdural hematoma the occurrence of seizures probably signifies associated brain injury. In brain abscess, seizures occurred early in the course of the disease in 50 per cent of patients but usually soon disappeared. Months or years later, recurring epileptic attacks might appear due to the cicatrix that had resulted from the abscess." @default.
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• W2157944286 date "1948-04-01" @default.
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• W2157944286 title "Focal Epilepsy: Correlation of the Pathological and Radiological Findings" @default.
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• W2157944286 doi "https://doi.org/10.1148/50.4.439" @default.
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