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• W2157947476 abstract "Norovirus causes epidemic gastroenteritis. The extent of excess mortality related to norovirus infections is not established and factors that influence the duration of viral shedding have not been determined. The aims of this thesis were (i) to describe the mortality among hospitalised patients with norovirus enteritis (NVE), (ii) to identify factors that indicate an increased mortality risk and a prolonged duration of viral shedding, and (iii) to examine if rectal swab samples can be used for the diagnosis of norovirus infection. In paper I, we retrospectively studied 598 adult hospitalised patients with gastroenteritis and a stool sample positive for norovirus. For ages >80 years, 30-day mortality was higher among patients with community-onset NVE, compared to patients with hospital-onset NVE and to matched controls. In paper II, 82 patients with community-onset NVE were included. The adjusted odds ratio for death within 30 days was 2.5 for one mmol/L increase in the venous lactate measured on arrival to the emergency department. Paper III presents a prospective study of 28 patients admitted with NVE. Rectal swab samples were obtained weekly during follow-up. Slow clearance of norovirus was associated with low serum levels of the chemokine CCL5 and high viral load. In paper IV, PCR was performed on paired rectal swab and stool samples, obtained simultaneously from 69 patients with suspected viral gastroenteritis. In 38 sample pairs virus was detected in both samples. One pair was stool+/swab− and one pair was stool−/swab+. In conclusion, norovirus infection may be associated with increased short-term mortality. Venous lactate can be used to identify patients with high mortality risk and a low level of CCL5 is associated with a long duration of viral shedding. Rectal swab samples can be used to diagnose norovirus infections." @default.
• W2157947476 created "2016-06-24" @default.
• W2157947476 creator A5038296965 @default.
• W2157947476 date "2014-12-02" @default.
• W2157947476 modified "2023-09-27" @default.
• W2157947476 title "On morbidity and mortality in novovirus infection" @default.
• W2157947476 cites W132617802 @default.
• W2157947476 cites W1500897436 @default.
• W2157947476 cites W1503494916 @default.
• W2157947476 cites W1573702528 @default.
• W2157947476 cites W1759089855 @default.
• W2157947476 cites W1804613345 @default.
• W2157947476 cites W1908548199 @default.
• W2157947476 cites W1924246380 @default.
• W2157947476 cites W194351578 @default.
• W2157947476 cites W1951854256 @default.
• W2157947476 cites W1963828325 @default.
• W2157947476 cites W1966065856 @default.
• W2157947476 cites W1968129428 @default.
• W2157947476 cites W1969272184 @default.
• W2157947476 cites W1969792304 @default.
• W2157947476 cites W1971515283 @default.
• W2157947476 cites W1972269714 @default.
• W2157947476 cites W1973182835 @default.
• W2157947476 cites W1978271621 @default.
• W2157947476 cites W1985635427 @default.
• W2157947476 cites W1988717380 @default.
• W2157947476 cites W1988912949 @default.
• W2157947476 cites W1990281803 @default.
• W2157947476 cites W1992332433 @default.
• W2157947476 cites W1998368194 @default.
• W2157947476 cites W1999638070 @default.
• W2157947476 cites W2000445173 @default.
• W2157947476 cites W2003078275 @default.
• W2157947476 cites W2005796452 @default.
• W2157947476 cites W2007292577 @default.
• W2157947476 cites W2008009415 @default.
• W2157947476 cites W2009898638 @default.
• W2157947476 cites W2011195546 @default.
• W2157947476 cites W2011925077 @default.
• W2157947476 cites W2013789930 @default.
• W2157947476 cites W2014075152 @default.
• W2157947476 cites W2015411778 @default.
• W2157947476 cites W2016808620 @default.
• W2157947476 cites W2017228144 @default.
• W2157947476 cites W2017264695 @default.
• W2157947476 cites W2020042607 @default.
• W2157947476 cites W2021347946 @default.
• W2157947476 cites W2021802517 @default.
• W2157947476 cites W2023134844 @default.
• W2157947476 cites W2024948981 @default.
• W2157947476 cites W2025733005 @default.
• W2157947476 cites W2030096101 @default.
• W2157947476 cites W2031978755 @default.
• W2157947476 cites W2037013112 @default.
• W2157947476 cites W2039540399 @default.
• W2157947476 cites W2044999792 @default.
• W2157947476 cites W2046001565 @default.
• W2157947476 cites W2049491684 @default.
• W2157947476 cites W2052994688 @default.
• W2157947476 cites W2055571966 @default.
• W2157947476 cites W2057022620 @default.
• W2157947476 cites W2063650753 @default.
• W2157947476 cites W2064482808 @default.
• W2157947476 cites W2068115215 @default.
• W2157947476 cites W2069870355 @default.
• W2157947476 cites W2071570482 @default.
• W2157947476 cites W2072408718 @default.
• W2157947476 cites W2076206717 @default.
• W2157947476 cites W2078215009 @default.
• W2157947476 cites W2080347641 @default.
• W2157947476 cites W2081681634 @default.
• W2157947476 cites W2085268948 @default.
• W2157947476 cites W2094312120 @default.
• W2157947476 cites W2096058381 @default.
• W2157947476 cites W2097121562 @default.
• W2157947476 cites W2099211646 @default.
• W2157947476 cites W2099276390 @default.
• W2157947476 cites W2099814399 @default.
• W2157947476 cites W2099952022 @default.
• W2157947476 cites W2103340591 @default.
• W2157947476 cites W2103677042 @default.
• W2157947476 cites W2106048079 @default.
• W2157947476 cites W2106220752 @default.
• W2157947476 cites W2107463130 @default.
• W2157947476 cites W2108639727 @default.
• W2157947476 cites W2109581338 @default.
• W2157947476 cites W2110419726 @default.
• W2157947476 cites W2110775348 @default.
• W2157947476 cites W2113384172 @default.
• W2157947476 cites W2115151801 @default.
• W2157947476 cites W2115655922 @default.
• W2157947476 cites W2117486769 @default.
• W2157947476 cites W2120636282 @default.
• W2157947476 cites W2122305519 @default.
• W2157947476 cites W2122973465 @default.
• W2157947476 cites W2123806956 @default.
• W2157947476 cites W2124750213 @default.
• W2157947476 cites W2125283487 @default.
• W2157947476 cites W2125409540 @default.

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