Matches in SemOpenAlex for { <https://semopenalex.org/work/W2157970175> ?p ?o ?g. }
- W2157970175 endingPage "784" @default.
- W2157970175 startingPage "749" @default.
- W2157970175 abstract "The human intestinal absorption of 241 drugs was evaluated. Three main methods were used to determine the human intestinal absorption: bioavailability, percentage of urinary excretion of drug‐related material following oral administration, and the ratio of cumulative urinary excretion of drug‐related material following oral and intravenous administration. The general solvation equation developed by Abraham's group was used to model the human intestinal absorption data of 169 drugs we considered to have reliable data. The model contains five Abraham descriptors calculated by the ABSOLV program. The results show that Abraham descriptors can successfully predict human intestinal absorption if the human absorption data is carefully classified based on solubility and administration dose to humans. © 2001 Wiley‐Liss, Inc. and the American Pharmaceutical Association J Pharm Sci 90:749–784, 2001" @default.
- W2157970175 created "2016-06-24" @default.
- W2157970175 creator A5003760179 @default.
- W2157970175 creator A5012093239 @default.
- W2157970175 creator A5025783187 @default.
- W2157970175 creator A5027719735 @default.
- W2157970175 creator A5038451838 @default.
- W2157970175 creator A5040095742 @default.
- W2157970175 creator A5041938358 @default.
- W2157970175 creator A5046226558 @default.
- W2157970175 creator A5052600092 @default.
- W2157970175 creator A5070620868 @default.
- W2157970175 creator A5088794437 @default.
- W2157970175 date "2001-06-01" @default.
- W2157970175 modified "2023-10-12" @default.
- W2157970175 title "Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure–activity relationship (QSAR) with the Abraham descriptors" @default.
- W2157970175 cites W100687419 @default.
- W2157970175 cites W126352625 @default.
- W2157970175 cites W126929050 @default.
- W2157970175 cites W1424161198 @default.
- W2157970175 cites W144174057 @default.
- W2157970175 cites W1489601464 @default.
- W2157970175 cites W1499839181 @default.
- W2157970175 cites W1501546570 @default.
- W2157970175 cites W1520727604 @default.
- W2157970175 cites W1522305291 @default.
- W2157970175 cites W1525975143 @default.
- W2157970175 cites W1535948728 @default.
- W2157970175 cites W155868167 @default.
- W2157970175 cites W1574019439 @default.
- W2157970175 cites W1584324651 @default.
- W2157970175 cites W1911592487 @default.
- W2157970175 cites W19162607 @default.
- W2157970175 cites W1920495182 @default.
- W2157970175 cites W1966632359 @default.
- W2157970175 cites W1968116841 @default.
- W2157970175 cites W1969180133 @default.
- W2157970175 cites W1969606959 @default.
- W2157970175 cites W1969822824 @default.
- W2157970175 cites W1970234230 @default.
- W2157970175 cites W1970766892 @default.
- W2157970175 cites W1971058600 @default.
- W2157970175 cites W1971748087 @default.
- W2157970175 cites W1971917311 @default.
- W2157970175 cites W1972411675 @default.
- W2157970175 cites W1979196526 @default.
- W2157970175 cites W1979890524 @default.
- W2157970175 cites W1980000380 @default.
- W2157970175 cites W1980751825 @default.
- W2157970175 cites W1980766303 @default.
- W2157970175 cites W1982908290 @default.
- W2157970175 cites W1985385907 @default.
- W2157970175 cites W1988388766 @default.
- W2157970175 cites W1989296532 @default.
- W2157970175 cites W1989329772 @default.
- W2157970175 cites W1989890831 @default.
- W2157970175 cites W1990057891 @default.
- W2157970175 cites W1990168476 @default.
- W2157970175 cites W1991201604 @default.
- W2157970175 cites W1991619186 @default.
- W2157970175 cites W1991628233 @default.
- W2157970175 cites W1991630564 @default.
- W2157970175 cites W1992166050 @default.
- W2157970175 cites W1992723295 @default.
- W2157970175 cites W1992942597 @default.
- W2157970175 cites W1994235820 @default.
- W2157970175 cites W1994772737 @default.
- W2157970175 cites W1995103763 @default.
- W2157970175 cites W1995183155 @default.
- W2157970175 cites W1996783775 @default.
- W2157970175 cites W1997496598 @default.
- W2157970175 cites W1998311030 @default.
- W2157970175 cites W1998405034 @default.
- W2157970175 cites W1999754683 @default.
- W2157970175 cites W1999796538 @default.
- W2157970175 cites W2000524760 @default.
- W2157970175 cites W2000662787 @default.
- W2157970175 cites W2001346172 @default.
- W2157970175 cites W2001961535 @default.
- W2157970175 cites W2002098693 @default.
- W2157970175 cites W2002377386 @default.
- W2157970175 cites W2002533466 @default.
- W2157970175 cites W2002729409 @default.
- W2157970175 cites W2003573884 @default.
- W2157970175 cites W2003654564 @default.
- W2157970175 cites W2003873735 @default.
- W2157970175 cites W2004680150 @default.
- W2157970175 cites W2004785370 @default.
- W2157970175 cites W2005877462 @default.
- W2157970175 cites W2007196783 @default.
- W2157970175 cites W2007980477 @default.
- W2157970175 cites W2008398527 @default.
- W2157970175 cites W2008495685 @default.
- W2157970175 cites W2008969964 @default.
- W2157970175 cites W2009740943 @default.
- W2157970175 cites W2010862754 @default.
- W2157970175 cites W2010929828 @default.
- W2157970175 cites W2011889873 @default.