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- W2158034722 endingPage "a015388" @default.
- W2158034722 startingPage "a015388" @default.
- W2158034722 abstract "Recent efforts in genomic research have enabled the characterization of molecular mechanisms underlying many types of cancers, ushering novel approaches for diagnosis and therapeutics. Melanoma is a molecularly heterogeneous disease, as many genetic alterations have been identified and the clinical features can vary. Although discoveries of frequent mutations including BRAF have already made clinically significant impact on patient care, there is a growing body of literature suggesting a role for additional mutations, driver and passenger types, in disease pathophysiology. Although some mutations have been strongly associated with clinical phenotypes of melanomas (such as physical distribution or morphologic subtype), the function or implications of many of the recently identified mutations remains less clear. The phenotypic and clinical impact of genomic mutations in melanoma remains a promising opportunity for progress in the care of melanoma patients." @default.
- W2158034722 created "2016-06-24" @default.
- W2158034722 creator A5015522380 @default.
- W2158034722 creator A5017303827 @default.
- W2158034722 date "2014-09-01" @default.
- W2158034722 modified "2023-10-15" @default.
- W2158034722 title "Melanoma: Clinical Features and Genomic Insights" @default.
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