FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158041303> ?p ?o ?g. }

• W2158041303 endingPage "e107" @default.
• W2158041303 startingPage "e102" @default.
• W2158041303 abstract "Rationale and objective Non-alcoholic fatty liver disease (NAFLD) is related to the metabolic syndrome and obesity. Proton magnetic resonance spectroscopy (1H MRS) is a non-invasive technique to assess hepatic triglyceride content (HTGC) and allows assessment of unsaturated fatty acids (UFA). There is increasing evidence that hepatic UFA are associated with the development of NAFLD. Therefore the objective of this study was to assess hepatic UFA in patients with NAFLD using 1H MRS. Materials and methods We included 26 consecutive patients with deranged liver enzymes, with and without type 2 diabetes mellitus (DM2), suspected for NAFLD. Liver function and metabolic parameters were assessed. 1H MRS measurements were performed at 3.0 T. From the 1H MR spectra two ratios were calculated: ratio 1 (UFA); unsaturated fatty acid peak vs. reference water peak and ratio 2 (HTGC); total fatty acid peak vs. reference water peak. Results Twenty-six patients were included. In these patients hepatic UFA (ratio 1) correlated with AST/ALT ratio (r = −0.46, p = 0.02), glucose levels (r = 0.46, p = 0.018), HOMA-IR (r = 0.59, p = 0.004) and HTGC (r = 0.81, p < 0.001). In diabetic patients (n = 12) hepatic UFA correlated with alkaline phosphatase levels (r = 0.72, p = 0.01), HOMA-IR (r = 0.73, p = 0.01) and HTGC (r = 0.83, p = 0.002). Compared to non-diabetic patients with NAFLD, hepatic UFA levels were increased in patients with DM2 and NAFLD (0.032 vs. 0.014, p = 0.03). Conclusion Hepatic UFA can be assessed with 1H MRS. 1H MRS determined hepatic UFA correlate with clinical and metabolic parameters associated with NAFLD. Hepatic UFA are increased in patients with DM2. This study provides evidence for the use of non-invasive 1H MRS to assess hepatic UFA in vivo." @default.
• W2158041303 created "2016-06-24" @default.
• W2158041303 creator A5022556537 @default.
• W2158041303 creator A5028901537 @default.
• W2158041303 creator A5044769257 @default.
• W2158041303 creator A5060871241 @default.
• W2158041303 creator A5070504139 @default.
• W2158041303 creator A5071562148 @default.
• W2158041303 date "2010-08-01" @default.
• W2158041303 modified "2023-09-29" @default.
• W2158041303 title "Hepatic unsaturated fatty acids in patients with non-alcoholic fatty liver disease assessed by 3.0T MR spectroscopy" @default.
• W2158041303 cites W1571773551 @default.
• W2158041303 cites W1761603361 @default.
• W2158041303 cites W1966857788 @default.
• W2158041303 cites W1970531452 @default.
• W2158041303 cites W1982487504 @default.
• W2158041303 cites W1983181715 @default.
• W2158041303 cites W1986323764 @default.
• W2158041303 cites W1986498969 @default.
• W2158041303 cites W1997757017 @default.
• W2158041303 cites W2000924423 @default.
• W2158041303 cites W2002163127 @default.
• W2158041303 cites W2006162642 @default.
• W2158041303 cites W2011556186 @default.
• W2158041303 cites W2012616752 @default.
• W2158041303 cites W2023823431 @default.
• W2158041303 cites W2030532669 @default.
• W2158041303 cites W2039849925 @default.
• W2158041303 cites W2040109162 @default.
• W2158041303 cites W2040456345 @default.
• W2158041303 cites W2040538211 @default.
• W2158041303 cites W2044321106 @default.
• W2158041303 cites W2050385934 @default.
• W2158041303 cites W2050914105 @default.
• W2158041303 cites W2052981488 @default.
• W2158041303 cites W2056488785 @default.
• W2158041303 cites W2057151553 @default.
• W2158041303 cites W2062229924 @default.
• W2158041303 cites W2065788317 @default.
• W2158041303 cites W2068075000 @default.
• W2158041303 cites W2074985929 @default.
• W2158041303 cites W2077071754 @default.
• W2158041303 cites W2078078010 @default.
• W2158041303 cites W2079071183 @default.
• W2158041303 cites W2079378050 @default.
• W2158041303 cites W2081405075 @default.
• W2158041303 cites W2091965357 @default.
• W2158041303 cites W2093071246 @default.
• W2158041303 cites W2098620454 @default.
• W2158041303 cites W2102656403 @default.
• W2158041303 cites W2103156933 @default.
• W2158041303 cites W2123365823 @default.
• W2158041303 cites W2123650181 @default.
• W2158041303 cites W2130544939 @default.
• W2158041303 cites W2134326473 @default.
• W2158041303 cites W2156085826 @default.
• W2158041303 cites W2156538682 @default.
• W2158041303 cites W2156792510 @default.
• W2158041303 cites W2159469729 @default.
• W2158041303 cites W2163769778 @default.
• W2158041303 cites W2164183759 @default.
• W2158041303 cites W2166017140 @default.
• W2158041303 cites W2171172585 @default.
• W2158041303 cites W4293174684 @default.
• W2158041303 doi "https://doi.org/10.1016/j.ejrad.2009.12.033" @default.
• W2158041303 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20116951" @default.
• W2158041303 hasPublicationYear "2010" @default.
• W2158041303 type Work @default.
• W2158041303 sameAs 2158041303 @default.
• W2158041303 citedByCount "28" @default.
• W2158041303 countsByYear W21580413032012 @default.
• W2158041303 countsByYear W21580413032013 @default.
• W2158041303 countsByYear W21580413032014 @default.
• W2158041303 countsByYear W21580413032016 @default.
• W2158041303 countsByYear W21580413032017 @default.
• W2158041303 countsByYear W21580413032018 @default.
• W2158041303 countsByYear W21580413032019 @default.
• W2158041303 countsByYear W21580413032020 @default.
• W2158041303 countsByYear W21580413032021 @default.
• W2158041303 countsByYear W21580413032022 @default.
• W2158041303 countsByYear W21580413032023 @default.
• W2158041303 crossrefType "journal-article" @default.
• W2158041303 hasAuthorship W2158041303A5022556537 @default.
• W2158041303 hasAuthorship W2158041303A5028901537 @default.
• W2158041303 hasAuthorship W2158041303A5044769257 @default.
• W2158041303 hasAuthorship W2158041303A5060871241 @default.
• W2158041303 hasAuthorship W2158041303A5070504139 @default.
• W2158041303 hasAuthorship W2158041303A5071562148 @default.
• W2158041303 hasConcept C126322002 @default.
• W2158041303 hasConcept C134018914 @default.
• W2158041303 hasConcept C160160445 @default.
• W2158041303 hasConcept C181199279 @default.
• W2158041303 hasConcept C185592680 @default.
• W2158041303 hasConcept C2776175330 @default.
• W2158041303 hasConcept C2778163477 @default.
• W2158041303 hasConcept C2778772119 @default.
• W2158041303 hasConcept C2778913445 @default.
• W2158041303 hasConcept C2779134260 @default.

• next