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- W2158069622 abstract "Mutants resistant to the phenanthrene alkaloids tylophorine, tylocrebrine, and cryptopleurine have been isolated from the yeast Saccharomyces cerevisiae . A single recessive nuclear gene was responsible for resistance. This resistance locus, cry , was closely linked to the mating locus (2.2 centimorgans). The resistance was ribosomal and was due to an altered 40 S ribosomal subunit. The mode of action of these drugs has been examined, and they appear to inhibit the translocation phase of protein synthesis." @default.
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- W2158069622 date "1974-12-01" @default.
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- W2158069622 title "Cryptopleurine Resistance: Genetic Locus for a 40 <i>S</i> Ribosomal Component in <i>Saccharomyces cerevisiae</i>" @default.
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- W2158069622 doi "https://doi.org/10.1128/jb.120.3.1308-1314.1974" @default.
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