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• W2158091421 abstract "Allergic rhinitis is a common disorder and involves the reaction to environmental allergens with resultant nasal and eye symptoms. The pathophysiologic mechanisms of the eye symptoms in allergic conjunctivitis include a direct effect on the eye by deposited allergen and indirect effects related to the deposition of allergen in the nasal mucosa. One of these proposed mechanisms is the existence of a nasal-ocular reflex whereby the nasal allergic reaction leads to an afferent reflex response, the efferent limb of which results in eye symptoms. Among the treatments available for allergic rhinitis, intranasal steroids are most efficacious for nasal symptoms and have also shown sizeable efficacy related to eye symptoms. We speculated that the effect of intranasal steroids on eye symptoms in allergic rhinitis was related to their inhibition of the nasal-ocular reflex and present data previously generated from our laboratory to support this assumption in a nasal challenge model." @default.
• W2158091421 created "2016-06-24" @default.
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• W2158091421 creator A5019002537 @default.
• W2158091421 date "2011-01-01" @default.
• W2158091421 modified "2023-09-27" @default.
• W2158091421 title "Nasal-Ocular Reflexes and Their Role in the Management of Allergic Rhinoconjunctivitis With Intranasal Steroids" @default.
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• W2158091421 doi "https://doi.org/10.1097/wox.0b013e3181f32dcd" @default.
• W2158091421 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3666181" @default.
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