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- W2158156721 abstract "Neurophysiological measures indicate cortical sensitivity to speech sounds by 150 ms after stimulus onset. In this time window dyslexic subjects start to show abnormal cortical processing. We investigated whether phonetic analysis is reflected in the robust auditory cortical activation at approximately 100 ms (N100m), and whether dyslexic subjects show abnormal N100m responses to speech or nonspeech sounds. We used magnetoencephalography to record auditory responses of 10 normally reading and 10 dyslexic adults. The speech stimuli were synthetic Finnish speech sounds (/a/, /u/, /pa/, /ka/). The nonspeech stimuli were complex nonspeech sounds and simple sine wave tones, composed of the F1+F2+F3 and F2 formant frequencies of the speech sounds, respectively. All sounds evoked a prominent N100m response in the bilateral auditory cortices. The N100m activation was stronger to speech than nonspeech sounds in the left but not in the right auditory cortex, in both subject groups. The leftward shift of hemispheric balance for speech sounds is likely to reflect analysis at the phonetic level. In dyslexic subjects the overall interhemispheric amplitude balance and timing were altered for all sound types alike. Dyslexic individuals thus seem to have an unusual cortical organization of general auditory processing in the time window of speech-sensitive analysis." @default.
- W2158156721 created "2016-06-24" @default.
- W2158156721 creator A5025172920 @default.
- W2158156721 creator A5081447890 @default.
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- W2158156721 date "2004-11-24" @default.
- W2158156721 modified "2023-09-25" @default.
- W2158156721 title "Cortical differentiation of speech and nonspeech sounds at 100 ms: implications for dyslexia" @default.
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- W2158156721 doi "https://doi.org/10.1093/cercor/bhh206" @default.
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- W2158156721 hasPublicationYear "2004" @default.
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