Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158177613> ?p ?o ?g. }
- W2158177613 endingPage "215" @default.
- W2158177613 startingPage "209" @default.
- W2158177613 abstract "Reported rates of non-small cell lung cancer (NSCLC) nodal failure following stereotactic body radiation therapy (SBRT) are lower than those reported in the surgical series when matched for stage. We hypothesized that this effect was due to incidental prophylactic nodal irradiation.A prospectively collected group of medically inoperable early stage NSCLC patients from 2004 to 2010 was used to identify cases with nodal relapses. Controls were matched to cases, 2:1, controlling for tumor volume (ie, same or greater) and tumor location (ie, same lobe). Reference (normalized to equivalent dose for 2-Gy fractions [EQD2]) point doses at the ipsilateral hilum and carina, demographic data, and clinical outcomes were extracted from the medical records. Univariate conditional logistical regression analyses were performed with variables of interest.Cases and controls were well matched except for size. The controls, as expected, had larger gross tumor volumes (P=.02). The mean ipsilateral hilar doses were 9.6 Gy and 22.4 Gy for cases and controls, respectively (P=.014). The mean carinal doses were 7.0 Gy and 9.2 Gy, respectively (P=.13). Mediastinal nodal relapses, with and without ipsilateral hilar relapse, were associated with mean ipsilateral hilar doses of 3.6 Gy and 19.8 Gy, respectively (P=.01). The conditional density plot appears to demonstrate an inverse dose-effect relationship between ipsilateral hilar normalized total dose and risk of ipsilateral hilar relapse.Incidental hilar dose greater than 20 Gy is significantly associated with fewer ipsilateral hilar relapses in inoperable early stage NSCLC patients treated with SBRT." @default.
- W2158177613 created "2016-06-24" @default.
- W2158177613 creator A5010067099 @default.
- W2158177613 creator A5016180818 @default.
- W2158177613 creator A5020447959 @default.
- W2158177613 creator A5030375757 @default.
- W2158177613 creator A5036264046 @default.
- W2158177613 creator A5039575432 @default.
- W2158177613 creator A5040285878 @default.
- W2158177613 creator A5078390519 @default.
- W2158177613 creator A5080668859 @default.
- W2158177613 date "2014-09-01" @default.
- W2158177613 modified "2023-10-01" @default.
- W2158177613 title "Incidental Prophylactic Nodal Irradiation and Patterns of Nodal Relapse in Inoperable Early Stage NSCLC Patients Treated With SBRT: A Case-Matched Analysis" @default.
- W2158177613 cites W1966290775 @default.
- W2158177613 cites W1978326675 @default.
- W2158177613 cites W1988582789 @default.
- W2158177613 cites W2010285845 @default.
- W2158177613 cites W2015096497 @default.
- W2158177613 cites W2016295772 @default.
- W2158177613 cites W2016804475 @default.
- W2158177613 cites W2017527202 @default.
- W2158177613 cites W2020037176 @default.
- W2158177613 cites W2025989218 @default.
- W2158177613 cites W2039054895 @default.
- W2158177613 cites W2040211532 @default.
- W2158177613 cites W2049681888 @default.
- W2158177613 cites W2062436298 @default.
- W2158177613 cites W2063247340 @default.
- W2158177613 cites W2063462142 @default.
- W2158177613 cites W2075161134 @default.
- W2158177613 cites W2076316116 @default.
- W2158177613 cites W2077058846 @default.
- W2158177613 cites W2077662539 @default.
- W2158177613 cites W2078150892 @default.
- W2158177613 cites W2082414365 @default.
- W2158177613 cites W2100101054 @default.
- W2158177613 cites W2106893486 @default.
- W2158177613 cites W2108789863 @default.
- W2158177613 cites W2112097252 @default.
- W2158177613 cites W2112744338 @default.
- W2158177613 cites W2115646671 @default.
- W2158177613 cites W2130467268 @default.
- W2158177613 cites W2141938478 @default.
- W2158177613 cites W2150152035 @default.
- W2158177613 cites W2169872250 @default.
- W2158177613 doi "https://doi.org/10.1016/j.ijrobp.2014.05.006" @default.
- W2158177613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24997639" @default.
- W2158177613 hasPublicationYear "2014" @default.
- W2158177613 type Work @default.
- W2158177613 sameAs 2158177613 @default.
- W2158177613 citedByCount "27" @default.
- W2158177613 countsByYear W21581776132015 @default.
- W2158177613 countsByYear W21581776132016 @default.
- W2158177613 countsByYear W21581776132017 @default.
- W2158177613 countsByYear W21581776132018 @default.
- W2158177613 countsByYear W21581776132019 @default.
- W2158177613 countsByYear W21581776132020 @default.
- W2158177613 countsByYear W21581776132021 @default.
- W2158177613 countsByYear W21581776132022 @default.
- W2158177613 countsByYear W21581776132023 @default.
- W2158177613 crossrefType "journal-article" @default.
- W2158177613 hasAuthorship W2158177613A5010067099 @default.
- W2158177613 hasAuthorship W2158177613A5016180818 @default.
- W2158177613 hasAuthorship W2158177613A5020447959 @default.
- W2158177613 hasAuthorship W2158177613A5030375757 @default.
- W2158177613 hasAuthorship W2158177613A5036264046 @default.
- W2158177613 hasAuthorship W2158177613A5039575432 @default.
- W2158177613 hasAuthorship W2158177613A5040285878 @default.
- W2158177613 hasAuthorship W2158177613A5078390519 @default.
- W2158177613 hasAuthorship W2158177613A5080668859 @default.
- W2158177613 hasConcept C126322002 @default.
- W2158177613 hasConcept C126838900 @default.
- W2158177613 hasConcept C126894567 @default.
- W2158177613 hasConcept C144301174 @default.
- W2158177613 hasConcept C146357865 @default.
- W2158177613 hasConcept C151730666 @default.
- W2158177613 hasConcept C2776256026 @default.
- W2158177613 hasConcept C2779819216 @default.
- W2158177613 hasConcept C2989005 @default.
- W2158177613 hasConcept C38180746 @default.
- W2158177613 hasConcept C509974204 @default.
- W2158177613 hasConcept C71924100 @default.
- W2158177613 hasConcept C86803240 @default.
- W2158177613 hasConceptScore W2158177613C126322002 @default.
- W2158177613 hasConceptScore W2158177613C126838900 @default.
- W2158177613 hasConceptScore W2158177613C126894567 @default.
- W2158177613 hasConceptScore W2158177613C144301174 @default.
- W2158177613 hasConceptScore W2158177613C146357865 @default.
- W2158177613 hasConceptScore W2158177613C151730666 @default.
- W2158177613 hasConceptScore W2158177613C2776256026 @default.
- W2158177613 hasConceptScore W2158177613C2779819216 @default.
- W2158177613 hasConceptScore W2158177613C2989005 @default.
- W2158177613 hasConceptScore W2158177613C38180746 @default.
- W2158177613 hasConceptScore W2158177613C509974204 @default.
- W2158177613 hasConceptScore W2158177613C71924100 @default.
- W2158177613 hasConceptScore W2158177613C86803240 @default.
- W2158177613 hasIssue "1" @default.