FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158179945> ?p ?o ?g. }

• W2158179945 endingPage "406" @default.
• W2158179945 startingPage "397" @default.
• W2158179945 abstract "Despite aggressive surgical and chemotherapeutic interventions, non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death in men and women with overall cure rates of less than 15%. Recent advances in our understanding of cellular signalling and its critical role in tumorigenesis has led to the development of novel therapies which may offer new hope. In particular, the epidermal growth-factor receptor superfamily is an attractive therapeutic target because it is commonly overexpressed in malignant disease, regulates many vital cellular processes, and seems to be a negative prognostic indicator. Several selective inhibitors of this family of receptors are currently being evaluated in several cancers including NSCLC. In this review we examine current preclinical and clinical evidence on monoclonal antibodies (cetuximab, ABX-EGF, EMD72000, MAb ICR62, h-R3, MDX-447, MDX-H210, trastuzumab, and 2C4), immunoconjugates (Y10, Ua30:2, Mab806), anti-EGF vaccine (YMB2000), and tyrosine kinase inhibitors (gefitinib, erlotinib, CI1033, GW572016, EKB 569, PKI166, PD158780, and TAK 165)." @default.
• W2158179945 created "2016-06-24" @default.
• W2158179945 creator A5044291041 @default.
• W2158179945 creator A5044972820 @default.
• W2158179945 creator A5075347427 @default.
• W2158179945 date "2003-07-01" @default.
• W2158179945 modified "2023-10-16" @default.
• W2158179945 title "Inhibitors of epidermal-growth-factor receptors: a review of clinical research with a focus on non-small-cell lung cancer" @default.
• W2158179945 cites W170006903 @default.
• W2158179945 cites W1910586263 @default.
• W2158179945 cites W1970941198 @default.
• W2158179945 cites W1982729445 @default.
• W2158179945 cites W1989673664 @default.
• W2158179945 cites W1999828947 @default.
• W2158179945 cites W2002859032 @default.
• W2158179945 cites W2021716162 @default.
• W2158179945 cites W2029667363 @default.
• W2158179945 cites W2046596676 @default.
• W2158179945 cites W2049292021 @default.
• W2158179945 cites W2051699257 @default.
• W2158179945 cites W2059972525 @default.
• W2158179945 cites W2079574908 @default.
• W2158179945 cites W2088716222 @default.
• W2158179945 cites W2098532770 @default.
• W2158179945 cites W2107487953 @default.
• W2158179945 cites W2114291028 @default.
• W2158179945 cites W2125730396 @default.
• W2158179945 cites W2130652363 @default.
• W2158179945 cites W2135836172 @default.
• W2158179945 cites W2141475443 @default.
• W2158179945 cites W2142661339 @default.
• W2158179945 cites W2150059798 @default.
• W2158179945 cites W2155741470 @default.
• W2158179945 cites W2156670712 @default.
• W2158179945 cites W2167531081 @default.
• W2158179945 cites W2169748783 @default.
• W2158179945 cites W2232770029 @default.
• W2158179945 cites W2318605753 @default.
• W2158179945 cites W4236285365 @default.
• W2158179945 cites W4252374499 @default.
• W2158179945 doi "https://doi.org/10.1016/s1470-2045(03)01137-9" @default.
• W2158179945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12850190" @default.
• W2158179945 hasPublicationYear "2003" @default.
• W2158179945 type Work @default.
• W2158179945 sameAs 2158179945 @default.
• W2158179945 citedByCount "267" @default.
• W2158179945 countsByYear W21581799452012 @default.
• W2158179945 countsByYear W21581799452013 @default.
• W2158179945 countsByYear W21581799452014 @default.
• W2158179945 countsByYear W21581799452015 @default.
• W2158179945 countsByYear W21581799452016 @default.
• W2158179945 countsByYear W21581799452017 @default.
• W2158179945 countsByYear W21581799452018 @default.
• W2158179945 countsByYear W21581799452019 @default.
• W2158179945 countsByYear W21581799452020 @default.
• W2158179945 countsByYear W21581799452021 @default.
• W2158179945 countsByYear W21581799452022 @default.
• W2158179945 countsByYear W21581799452023 @default.
• W2158179945 crossrefType "journal-article" @default.
• W2158179945 hasAuthorship W2158179945A5044291041 @default.
• W2158179945 hasAuthorship W2158179945A5044972820 @default.
• W2158179945 hasAuthorship W2158179945A5075347427 @default.
• W2158179945 hasConcept C121608353 @default.
• W2158179945 hasConcept C126322002 @default.
• W2158179945 hasConcept C143998085 @default.
• W2158179945 hasConcept C159654299 @default.
• W2158179945 hasConcept C170493617 @default.
• W2158179945 hasConcept C203014093 @default.
• W2158179945 hasConcept C2776256026 @default.
• W2158179945 hasConcept C2776362946 @default.
• W2158179945 hasConcept C2778087573 @default.
• W2158179945 hasConcept C2779438470 @default.
• W2158179945 hasConcept C2779786085 @default.
• W2158179945 hasConcept C2779998722 @default.
• W2158179945 hasConcept C2780580887 @default.
• W2158179945 hasConcept C2780806702 @default.
• W2158179945 hasConcept C42362537 @default.
• W2158179945 hasConcept C502942594 @default.
• W2158179945 hasConcept C526805850 @default.
• W2158179945 hasConcept C530470458 @default.
• W2158179945 hasConcept C542903549 @default.
• W2158179945 hasConcept C555283112 @default.
• W2158179945 hasConcept C71924100 @default.
• W2158179945 hasConceptScore W2158179945C121608353 @default.
• W2158179945 hasConceptScore W2158179945C126322002 @default.
• W2158179945 hasConceptScore W2158179945C143998085 @default.
• W2158179945 hasConceptScore W2158179945C159654299 @default.
• W2158179945 hasConceptScore W2158179945C170493617 @default.
• W2158179945 hasConceptScore W2158179945C203014093 @default.
• W2158179945 hasConceptScore W2158179945C2776256026 @default.
• W2158179945 hasConceptScore W2158179945C2776362946 @default.
• W2158179945 hasConceptScore W2158179945C2778087573 @default.
• W2158179945 hasConceptScore W2158179945C2779438470 @default.
• W2158179945 hasConceptScore W2158179945C2779786085 @default.
• W2158179945 hasConceptScore W2158179945C2779998722 @default.
• W2158179945 hasConceptScore W2158179945C2780580887 @default.
• W2158179945 hasConceptScore W2158179945C2780806702 @default.
• W2158179945 hasConceptScore W2158179945C42362537 @default.

• next