FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158186770> ?p ?o ?g. }

• W2158186770 endingPage "1990" @default.
• W2158186770 startingPage "1986" @default.
• W2158186770 abstract "2',3'-Dideoxy-3'-fluorothymidine (FddThd), 2',3'-didehydro-2',3'- dideoxythymidine (ddeThd), and 3'-fluoro-5-methyl-deoxycytidine (FddMeCyt) are, in their triphosphate forms, selective inhibitors of human immunodeficiency virus type 1 reverse transcriptase. We report that 0.3 microM FddThd, FddMeCyt, or ddeThd as well as 3'-chloro-5-methyl-deoxycytidine (ClddMeCyt) or 3'-amino-5-methyl-deoxycytidine (AddMeCyt) almost completely blocked production of hepatitis B virus (HBV) particles by HBV DNA-transfected cell line 2.2.15 in vitro. Only at an at least 10-fold-higher concentration was a cytotoxic effect observed. These results indicate that FddThd, FddMeCyt, ClddMeCyt, AddMeCyt, and ddeThd are potent anti-HBV agents in vitro." @default.
• W2158186770 created "2016-06-24" @default.
• W2158186770 creator A5033825199 @default.
• W2158186770 creator A5034107660 @default.
• W2158186770 creator A5034644142 @default.
• W2158186770 creator A5045183956 @default.
• W2158186770 creator A5051235946 @default.
• W2158186770 creator A5074023473 @default.
• W2158186770 creator A5083958793 @default.
• W2158186770 creator A5086108824 @default.
• W2158186770 date "1990-10-01" @default.
• W2158186770 modified "2023-09-26" @default.
• W2158186770 title "Potent inhibition of hepatitis B virus production in vitro by modified pyrimidine nucleosides" @default.
• W2158186770 cites W1508971325 @default.
• W2158186770 cites W1629361626 @default.
• W2158186770 cites W1780716740 @default.
• W2158186770 cites W1795551994 @default.
• W2158186770 cites W1964049449 @default.
• W2158186770 cites W1967446284 @default.
• W2158186770 cites W1967999707 @default.
• W2158186770 cites W1981342096 @default.
• W2158186770 cites W1983903823 @default.
• W2158186770 cites W2003916038 @default.
• W2158186770 cites W2008736019 @default.
• W2158186770 cites W2010338556 @default.
• W2158186770 cites W2017076163 @default.
• W2158186770 cites W2018501180 @default.
• W2158186770 cites W2023506562 @default.
• W2158186770 cites W2029987769 @default.
• W2158186770 cites W2052794617 @default.
• W2158186770 cites W2058831749 @default.
• W2158186770 cites W2087013767 @default.
• W2158186770 cites W2087023969 @default.
• W2158186770 cites W2102315942 @default.
• W2158186770 cites W2104073003 @default.
• W2158186770 cites W2119282315 @default.
• W2158186770 cites W2150090065 @default.
• W2158186770 cites W4255162860 @default.
• W2158186770 cites W2045805560 @default.
• W2158186770 doi "https://doi.org/10.1128/aac.34.10.1986" @default.
• W2158186770 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/171976" @default.
• W2158186770 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2291664" @default.
• W2158186770 hasPublicationYear "1990" @default.
• W2158186770 type Work @default.
• W2158186770 sameAs 2158186770 @default.
• W2158186770 citedByCount "28" @default.
• W2158186770 countsByYear W21581867702019 @default.
• W2158186770 crossrefType "journal-article" @default.
• W2158186770 hasAuthorship W2158186770A5033825199 @default.
• W2158186770 hasAuthorship W2158186770A5034107660 @default.
• W2158186770 hasAuthorship W2158186770A5034644142 @default.
• W2158186770 hasAuthorship W2158186770A5045183956 @default.
• W2158186770 hasAuthorship W2158186770A5051235946 @default.
• W2158186770 hasAuthorship W2158186770A5074023473 @default.
• W2158186770 hasAuthorship W2158186770A5083958793 @default.
• W2158186770 hasAuthorship W2158186770A5086108824 @default.
• W2158186770 hasBestOaLocation W21581867701 @default.
• W2158186770 hasConcept C153911025 @default.
• W2158186770 hasConcept C154317977 @default.
• W2158186770 hasConcept C159047783 @default.
• W2158186770 hasConcept C185592680 @default.
• W2158186770 hasConcept C202751555 @default.
• W2158186770 hasConcept C2522874641 @default.
• W2158186770 hasConcept C2776543447 @default.
• W2158186770 hasConcept C2776694085 @default.
• W2158186770 hasConcept C2777844706 @default.
• W2158186770 hasConcept C2780258809 @default.
• W2158186770 hasConcept C2780593183 @default.
• W2158186770 hasConcept C54355233 @default.
• W2158186770 hasConcept C55493867 @default.
• W2158186770 hasConcept C81885089 @default.
• W2158186770 hasConcept C86803240 @default.
• W2158186770 hasConceptScore W2158186770C153911025 @default.
• W2158186770 hasConceptScore W2158186770C154317977 @default.
• W2158186770 hasConceptScore W2158186770C159047783 @default.
• W2158186770 hasConceptScore W2158186770C185592680 @default.
• W2158186770 hasConceptScore W2158186770C202751555 @default.
• W2158186770 hasConceptScore W2158186770C2522874641 @default.
• W2158186770 hasConceptScore W2158186770C2776543447 @default.
• W2158186770 hasConceptScore W2158186770C2776694085 @default.
• W2158186770 hasConceptScore W2158186770C2777844706 @default.
• W2158186770 hasConceptScore W2158186770C2780258809 @default.
• W2158186770 hasConceptScore W2158186770C2780593183 @default.
• W2158186770 hasConceptScore W2158186770C54355233 @default.
• W2158186770 hasConceptScore W2158186770C55493867 @default.
• W2158186770 hasConceptScore W2158186770C81885089 @default.
• W2158186770 hasConceptScore W2158186770C86803240 @default.
• W2158186770 hasIssue "10" @default.
• W2158186770 hasLocation W21581867701 @default.
• W2158186770 hasLocation W21581867702 @default.
• W2158186770 hasOpenAccess W2158186770 @default.
• W2158186770 hasPrimaryLocation W21581867701 @default.
• W2158186770 hasRelatedWork W1964955632 @default.
• W2158186770 hasRelatedWork W1979511395 @default.
• W2158186770 hasRelatedWork W2052483994 @default.
• W2158186770 hasRelatedWork W2076874973 @default.
• W2158186770 hasRelatedWork W2118787634 @default.
• W2158186770 hasRelatedWork W2140679976 @default.

• next