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• W2158202130 startingPage "3256" @default.
• W2158202130 abstract "Abstract The mitochondrial NADH:ubiquinone oxidoreductase complex (Complex I) is a large protein complex formed from both nuclearly and mitochondrially encoded subunits. Subunit ND1 is encoded by a mitochondrial gene comprising five exons, and the mature transcript requires four RNA splicing events, two of which involve trans-splicing independently transcribed RNAs. We have identified a nuclear gene (OTP43) absolutely required for trans-splicing of intron 1 (and only intron 1) of Arabidopsis thaliana nad1 transcripts. This gene encodes a previously uncharacterized pentatricopeptide repeat protein. Mutant Arabidopsis plants with a disrupted OTP43 gene do not present detectable mitochondrial Complex I activity and show severe defects in seed development, germination, and to a lesser extent in plant growth. The alternative respiratory pathway involving alternative oxidase is significantly induced in the mutant." @default.
• W2158202130 created "2016-06-24" @default.
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• W2158202130 creator A5050804853 @default.
• W2158202130 creator A5066623208 @default.
• W2158202130 date "2007-10-01" @default.
• W2158202130 modified "2023-10-11" @default.
• W2158202130 title "The Pentatricopeptide Repeat Gene<i>OTP43</i>Is Required for<i>trans</i>-Splicing of the Mitochondrial<i>nad1</i>Intron 1 in<i>Arabidopsis thaliana</i>" @default.
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• W2158202130 doi "https://doi.org/10.1105/tpc.107.054841" @default.
• W2158202130 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2174710" @default.
• W2158202130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17965268" @default.
• W2158202130 hasPublicationYear "2007" @default.
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