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- W2158366956 abstract "The association between sleep-disordered breathing (SDB) and stroke cannot be attributed to chance. Indeed, if a link between SDB and cardiovascular disease were demonstrated 1–5, the absence of a relationship with stroke would be surprising. Although we still lack definitive and consistent data from large epidemiological surveys, multiple studies using a variety of methodologies have shown a high prevalence of SDB following stroke, especially obstructive sleep apnoea (OSA) 6–13. This prevalence is greater than expected, bearing in mind the available epidemiological data 14, 15. Nevertheless, these data must be interpreted with caution since stroke patients have a high mean age and the number of obstructive events increases with age, without clinical relevance 16, 17. Moreover, case-control studies have also demonstrated a significantly higher prevalence of SDB in patients with stroke than in controls 8, 9, 11.SDB may be regarded as a consequence (mainly central events) 18, 19 or as a cause (mainly obstructive events) 13 of stroke. Given the availability of an effective and safe treatment for OSA 20–24, nasal continuous positive airway pressure (nCPAP) could modify the incidence of stroke (if SDB is regarded as a risk factor) or the outcome of these patients (if SDB is considered as a prognostic factor). In this issue, Wessendorf et al. 25 and Sandberg et al. 26 have endeavoured to treat stroke and SDB patients with nCPAP. The resulting data are the first to show a beneficial effect of this treatment in these patients, thereby suggesting the feasibility of introducing nCPAP in such patients, in whom cognitive impairment and physical disability may constitute important drawbacks, and in whom excessive daytime sleepiness does not always justify treatment 27. Despite concerns about some of …" @default.
- W2158366956 created "2016-06-24" @default.
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- W2158366956 date "2001-10-01" @default.
- W2158366956 modified "2023-10-15" @default.
- W2158366956 title "Sleep-disordered breathing and stroke: is there a rationale for treatment?" @default.
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- W2158366956 doi "https://doi.org/10.1183/09031936.01.00250201" @default.
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