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- W2158404435 abstract "The authors have described the synthetic way to new N-pyridinyl(methyl)indolylpropanamides acting as non acidic NSAIDs. Pharmacomodulation was carried out at N-1 and C-5 of the indole ring and at the level of the propanamide chain. N-(pyridin-3-ylmethyl)-3-[5-chloro-1-(4-chlorobenzyl)-indol-3-yl]propanamide 32 represents one of the most potent compounds evaluated in the TPA-induced mouse ear swelling assay, with a level of activity higher than that of ibuprofen and comparable to that of dexamethasone." @default.
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- W2158404435 date "2004-11-01" @default.
- W2158404435 modified "2023-09-28" @default.
- W2158404435 title "New N-pyridinyl(methyl)-indolalkanamides acting as topical inflammation inhibitors" @default.
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- W2158404435 doi "https://doi.org/10.1016/j.bmcl.2004.07.057" @default.
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