Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158425035> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2158425035 endingPage "1108" @default.
- W2158425035 startingPage "1102" @default.
- W2158425035 abstract "The aim of the present study was to test the influence of inhaled isotonic Ems salt (brine from the spa of Bad Ems, Germany) compared to isotonic saline on radioaerosol clearance (RC) in patients with chronic cough. Ems salt is an alkaline solution (pH 8.0-9.0) containing largely bicarbonate ions rather than the chloride ions present in isotonic saline (pH 6.4). RC was assessed with a radioaerosol technique using technetium-99m albumin in supine patients. After a 30-min baseline measurement of RC according to a single blind and randomized design, patients inhaled Ems salt (n=22, 20-77 yrs) or isotonic saline (n=21, 34-72 yrs) via a jet nebulizer (Pari Boy) for 10 min and were scanned for an additional 30 min. There was no difference between the two groups before intervention in terms of deposition pattern, lung function and baseline RC rate. After inhalation of Ems salt, the RC rate (1/tau) improved significantly from 0.15+/-0.14 (mean+/-SD) to 0.53+/-0.70 L.h(-1) (p<0.005); no change was found after isotonic saline (0.13+/-0.13 to 0.08+/-0.09 L.h(-1), NS). Voluntary coughs performed after 60 min had no effect on the RC rate. However, in the Ems salt group, significantly more patients reported an inhalation induced cough. Compared to the Ems salt patients, who did not cough during and after inhalation, the RC rate in the cough group was enhanced significantly (0.10+/-0.12 versus 0.73+/-0.83, p=0.017), this effect being seen more frequently in females (p=0.003). It is concluded that Ems salt improves radioaerosol clearance significantly in patients with chronic cough. The underlying mechanism, regarding whether induced cough, increased water content in the mucus or enhanced ciliary beat frequency is the leading cause of Ems salt action, remains unclear." @default.
- W2158425035 created "2016-06-24" @default.
- W2158425035 creator A5013544835 @default.
- W2158425035 creator A5022445495 @default.
- W2158425035 creator A5071933969 @default.
- W2158425035 creator A5083556024 @default.
- W2158425035 date "2000-12-01" @default.
- W2158425035 modified "2023-10-16" @default.
- W2158425035 title "Inhaled isotonic alkaline versus saline solution and radioaerosol clearance in chronic cough" @default.
- W2158425035 cites W1587089109 @default.
- W2158425035 cites W1974842765 @default.
- W2158425035 cites W2020431943 @default.
- W2158425035 cites W2035264294 @default.
- W2158425035 cites W2074855042 @default.
- W2158425035 cites W2121159616 @default.
- W2158425035 cites W2131792955 @default.
- W2158425035 cites W2155117843 @default.
- W2158425035 cites W2168454304 @default.
- W2158425035 cites W2184661031 @default.
- W2158425035 cites W2408923549 @default.
- W2158425035 cites W2412593843 @default.
- W2158425035 cites W2419559734 @default.
- W2158425035 cites W2526350037 @default.
- W2158425035 doi "https://doi.org/10.1034/j.1399-3003.2000.16f14.x" @default.
- W2158425035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11292113" @default.
- W2158425035 hasPublicationYear "2000" @default.
- W2158425035 type Work @default.
- W2158425035 sameAs 2158425035 @default.
- W2158425035 citedByCount "11" @default.
- W2158425035 countsByYear W21584250352018 @default.
- W2158425035 countsByYear W21584250352021 @default.
- W2158425035 countsByYear W21584250352022 @default.
- W2158425035 crossrefType "journal-article" @default.
- W2158425035 hasAuthorship W2158425035A5013544835 @default.
- W2158425035 hasAuthorship W2158425035A5022445495 @default.
- W2158425035 hasAuthorship W2158425035A5071933969 @default.
- W2158425035 hasAuthorship W2158425035A5083556024 @default.
- W2158425035 hasBestOaLocation W21584250351 @default.
- W2158425035 hasConcept C125567185 @default.
- W2158425035 hasConcept C126322002 @default.
- W2158425035 hasConcept C2776954882 @default.
- W2158425035 hasConcept C2777397205 @default.
- W2158425035 hasConcept C2780352487 @default.
- W2158425035 hasConcept C2781112554 @default.
- W2158425035 hasConcept C2910183285 @default.
- W2158425035 hasConcept C2910682862 @default.
- W2158425035 hasConcept C3017567848 @default.
- W2158425035 hasConcept C42219234 @default.
- W2158425035 hasConcept C71924100 @default.
- W2158425035 hasConcept C77056095 @default.
- W2158425035 hasConceptScore W2158425035C125567185 @default.
- W2158425035 hasConceptScore W2158425035C126322002 @default.
- W2158425035 hasConceptScore W2158425035C2776954882 @default.
- W2158425035 hasConceptScore W2158425035C2777397205 @default.
- W2158425035 hasConceptScore W2158425035C2780352487 @default.
- W2158425035 hasConceptScore W2158425035C2781112554 @default.
- W2158425035 hasConceptScore W2158425035C2910183285 @default.
- W2158425035 hasConceptScore W2158425035C2910682862 @default.
- W2158425035 hasConceptScore W2158425035C3017567848 @default.
- W2158425035 hasConceptScore W2158425035C42219234 @default.
- W2158425035 hasConceptScore W2158425035C71924100 @default.
- W2158425035 hasConceptScore W2158425035C77056095 @default.
- W2158425035 hasIssue "6" @default.
- W2158425035 hasLocation W21584250351 @default.
- W2158425035 hasLocation W21584250352 @default.
- W2158425035 hasOpenAccess W2158425035 @default.
- W2158425035 hasPrimaryLocation W21584250351 @default.
- W2158425035 hasRelatedWork W1964110542 @default.
- W2158425035 hasRelatedWork W1967259847 @default.
- W2158425035 hasRelatedWork W2319612484 @default.
- W2158425035 hasRelatedWork W2395396709 @default.
- W2158425035 hasRelatedWork W2416591235 @default.
- W2158425035 hasRelatedWork W2743764431 @default.
- W2158425035 hasRelatedWork W2782191914 @default.
- W2158425035 hasRelatedWork W4233127472 @default.
- W2158425035 hasRelatedWork W80296948 @default.
- W2158425035 hasRelatedWork W2747283129 @default.
- W2158425035 hasVolume "16" @default.
- W2158425035 isParatext "false" @default.
- W2158425035 isRetracted "false" @default.
- W2158425035 magId "2158425035" @default.
- W2158425035 workType "article" @default.