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- W2158490019 abstract "The first cardiac trans- plantation in the world was per- formed in 1967. Since then it has become standard therapy for end- stage heart failure with over 200 recipients in British Columbia over the past 20 years. Cardiac trans- plantation should be considered in individuals with advanced heart dis- ease who have a poor chance of long-term survival despite optimal medical or surgical therapy. Con- traindications to transplant include pulmonary hypertension, active in - fection, systemic illness, renal dys- function, recent malignancy, active smoking/substance abuse, or the inability to undergo rehabilitation. All patients require immunosuppres- sive therapy following transplanta- tion to prevent allograft rejection. In addition to rejection, common com- plications in the post-transplant period include infections, malignan- cy, post-transplant lymphoprolifera- tive disorder, and allograft coronary artery disease. Given the scarcity of available donor hearts in BC, efforts have been made recently to develop mechanical ventricular assist de - vices to support patients waiting for donor organs." @default.
- W2158490019 created "2016-06-24" @default.
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- W2158490019 date "2010-01-01" @default.
- W2158490019 modified "2023-09-27" @default.
- W2158490019 title "Cardiac transplantation in British Columbia Standard malignancy screening and aggressive management of atherosclerotic risk factors are both needed after a heart transplant." @default.
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