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• W2158520275 abstract "Digoxin has been a key therapeutic for heart failure and atrial tachyarrhythmias for over 200 years following Withering9s groundbreaking work depicting the therapeutic benefit of the common botanical foxglove in his 1785 monograph. The use of digoxin preceded any randomised evidence or even basic understanding of its mechanism of action. Over the past two decades, there has been mounting evidence further challenging the safety and efficacy of digoxin, while multiple other therapies for both heart failure and atrial tachyarrhythmias have proven to be more effective and safe. Altogether, digoxin still has an important role in contemporary pharmacotherapeutics, though its role remains controversial and should be reserved for selective patients and clinical situations, with careful attention to serum concentrations." @default.
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• W2158520275 date "2009-04-01" @default.
• W2158520275 modified "2023-10-10" @default.
• W2158520275 title "Treatment of Acute Renal Failure Secondary to Multiple Myeloma with Chemotherapy and Extended High Cut-Off Hemodialysis" @default.
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• W2158520275 doi "https://doi.org/10.2215/cjn.04590908" @default.
• W2158520275 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2666427" @default.
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