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• W2158542439 abstract "This study investigated the combined effects of endurance training and aging on substrate oxidation during exercise. Thirty-one healthy male subjects in 4 groups (8 middle-aged trained cyclists, 8 young trained cyclists, 7 middle-aged sedentary men, and 8 young sedentary men) performed 2 50-minute cycle ergometer exercise tests, below and above (±15%) their individual ventilatory threshold (VT). Substrate oxidation was evaluated by indirect calorimetry during the steady-state tests. Aging decreased carbohydrate (CHO) use (P < .05) in all subjects regardless of fitness status or exercise intensity. However, it declined 2-fold less in the trained men (P < .05) and was associated with a stronger epinephrine response (P < .05). During hard-intensity exercise, endurance training increased by 100% CHO use in the older men (P < .05). In the younger men, training increased fat oxidation but did not change CHO oxidation, resulting in a marked decrease in the ratio between CHO and fat used at high-intensity exercise (−93%; P < .05). These data suggest an age-related decline in the use of CHO as an energy source in exercising men, independent of intensity level. This decline, however, is attenuated in well-trained men for exercise intensities above the VT. In view of these findings, we hypothesize that cycling training performed at a specific exercise intensity (ie, 15% above VT) may improve CHO mobilization and use in middle-aged men." @default.
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• W2158542439 date "2005-11-01" @default.
• W2158542439 modified "2023-10-16" @default.
• W2158542439 title "Substrate oxidation during exercise at moderate and hard intensity in middle-aged and young athletes vs sedentary men" @default.
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• W2158542439 doi "https://doi.org/10.1016/j.metabol.2004.12.002" @default.
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