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- W2158551444 abstract "The responsiveness of lung parenchymal strips isolated from actively sensitized guinea pigs to some selected autacoids (histamine, 5-hydroxytryptamine, bradykinin, and prostaglandins F2 alpha and l2) and autonomic drugs (acetylcholine, norepinephrine, methoxamine, and isoprenaline) was compared with that of strips from unsensitized animals. The concentration-response curves to the agonists, with the only exception of isoprenaline, in the sensitized group exhibited a left upward displacement (greater maximal effects and less effective concentration 50%) compared with those obtained in the unsensitized group. These results indicate the existence of a nonspecific increase in responsiveness of lung parenchymal strip isolated from sensitized animals." @default.
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- W2158551444 date "1984-06-01" @default.
- W2158551444 modified "2023-10-18" @default.
- W2158551444 title "Hyperresponsiveness to autacoids and autonomic drugs in lung parenchymal strips from sensitized guinea pigs." @default.
- W2158551444 doi "https://doi.org/10.1164/arrd.1984.129.6.948" @default.
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