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• W2158587032 endingPage "4606" @default.
• W2158587032 startingPage "4590" @default.
• W2158587032 abstract "As sessile organisms, higher plants have evolved the capacity to sense and interpret diverse light signals to modulate their development. In Arabidopsis thaliana, low-intensity and long-wavelength UV-B light is perceived as an informational signal to mediate UV-B-induced photomorphogenesis. Here, we report that the multifunctional E3 ubiquitin ligase, CONSTITUTIVE PHOTOMORPHOGENESIS1 (COP1), a known key player in UV-B photomorphogenic responses, is also a UV-B-inducible gene. Two transcription factors, FAR-RED ELONGATED HYPOCOTYL3 (FHY3) and ELONGATED HYPOCOTYL5 (HY5), directly bind to distinct regulatory elements within the COP1 promoter, which are essential for the induction of the COP1 gene mediated by photomorphogenic UV-B signaling. Absence of FHY3 results in impaired UV-B-induced hypocotyl growth and reduced tolerance against damaging UV-B. Thus, FHY3 positively regulates UV-B-induced photomorphogenesis by directly activating COP1 transcription, while HY5 promotes COP1 expression via a positive feedback loop. Furthermore, FHY3 and HY5 physically interact with each other, and this interaction is diminished by UV-B. Together, our findings reveal that COP1 gene expression in response to photomorphogenic UV-B is controlled by a combinatorial regulation of FHY3 and HY5, and this UV-B-specific working mode of FHY3 and HY5 is distinct from that in far-red light and circadian conditions." @default.
• W2158587032 created "2016-06-24" @default.
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• W2158587032 date "2012-11-01" @default.
• W2158587032 modified "2023-10-12" @default.
• W2158587032 title "<i>Arabidopsis</i> FHY3 and HY5 Positively Mediate Induction of <i>COP1</i> Transcription in Response to Photomorphogenic UV-B Light" @default.
• W2158587032 cites W1551691749 @default.
• W2158587032 cites W1665182114 @default.
• W2158587032 cites W1763052962 @default.
• W2158587032 cites W1901396953 @default.
• W2158587032 cites W1946679520 @default.
• W2158587032 cites W1964926458 @default.
• W2158587032 cites W1964926620 @default.
• W2158587032 cites W1971706091 @default.
• W2158587032 cites W1973703105 @default.
• W2158587032 cites W1984934120 @default.
• W2158587032 cites W1989730190 @default.
• W2158587032 cites W1991881586 @default.
• W2158587032 cites W1993537846 @default.
• W2158587032 cites W1998587460 @default.
• W2158587032 cites W2001879779 @default.
• W2158587032 cites W2005577765 @default.
• W2158587032 cites W2006153112 @default.
• W2158587032 cites W2012955049 @default.
• W2158587032 cites W2014770852 @default.
• W2158587032 cites W2017398067 @default.
• W2158587032 cites W2019364309 @default.
• W2158587032 cites W2036271007 @default.
• W2158587032 cites W2036656803 @default.
• W2158587032 cites W2037480145 @default.
• W2158587032 cites W2044000436 @default.
• W2158587032 cites W2053539706 @default.
• W2158587032 cites W2053745008 @default.
• W2158587032 cites W2055906347 @default.
• W2158587032 cites W2060398106 @default.
• W2158587032 cites W2061119080 @default.
• W2158587032 cites W2083263204 @default.
• W2158587032 cites W2086934811 @default.
• W2158587032 cites W2092401751 @default.
• W2158587032 cites W2092785935 @default.
• W2158587032 cites W2097903157 @default.
• W2158587032 cites W2099267861 @default.
• W2158587032 cites W2100464344 @default.
• W2158587032 cites W2100744249 @default.
• W2158587032 cites W2100951456 @default.
• W2158587032 cites W2102481320 @default.
• W2158587032 cites W2103305929 @default.
• W2158587032 cites W2103621068 @default.
• W2158587032 cites W2105856873 @default.
• W2158587032 cites W2106495133 @default.
• W2158587032 cites W2110351078 @default.
• W2158587032 cites W2112826362 @default.
• W2158587032 cites W2112862529 @default.
• W2158587032 cites W2113127368 @default.
• W2158587032 cites W2115096842 @default.
• W2158587032 cites W2116791893 @default.
• W2158587032 cites W2125018901 @default.
• W2158587032 cites W2125495515 @default.
• W2158587032 cites W2126610272 @default.
• W2158587032 cites W2129452863 @default.
• W2158587032 cites W2129622260 @default.
• W2158587032 cites W2133685835 @default.
• W2158587032 cites W2133840666 @default.
• W2158587032 cites W2134030532 @default.
• W2158587032 cites W2135959854 @default.
• W2158587032 cites W2136218783 @default.
• W2158587032 cites W2138805658 @default.
• W2158587032 cites W2140918488 @default.
• W2158587032 cites W2141627485 @default.
• W2158587032 cites W2143275830 @default.
• W2158587032 cites W2148019935 @default.
• W2158587032 cites W2152324471 @default.
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• W2158587032 cites W2161064670 @default.
• W2158587032 cites W2164556705 @default.
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• W2158587032 cites W2165281550 @default.
• W2158587032 cites W2165402269 @default.
• W2158587032 cites W2167082201 @default.
• W2158587032 cites W2167222308 @default.
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• W2158587032 doi "https://doi.org/10.1105/tpc.112.103994" @default.
• W2158587032 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3531854" @default.
• W2158587032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23150635" @default.
• W2158587032 hasPublicationYear "2012" @default.
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