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• W2158595873 endingPage "577" @default.
• W2158595873 startingPage "564" @default.
• W2158595873 abstract "This article reviews the physico-chemical properties and performance characteristics of the two new potent inhaled anesthetics, desflurane and sevoflurane. Both drugs provide a greater degree of control of anesthetic depth and a more rapid immediate recovery from anesthesia than is currently available with other inhaled agents because of their decreased solubility. Desflurane is currently in widespread clinical use in the United States and parts of Europe. Compared with sevoflurane, it has the additional advantage of being extremely resistant to degradation and biotransformation. However, its pungent odor and tendency to irritate the respiratory tract make it unsuitable for inhalational inductions, and it has been linked to CO production in CO2 absorbents. The sympathetic nervous system activation that occurs with desflurane limits its use in patients with cardiac disease. Otherwise, its hemodynamic and physiologic effects are similar to those seen with isoflurane. Studies of the economics of using desflurane are mixed, although it may offer the advantage of shorter postoperative recovery time. Sevoflurane is currently in widespread clinical use in Japan and parts of South America. The FDA Advisory Panel has recently recommended approval of sevoflurane in the United States, and we can expect the drug to be clinically available in the United States in the second quarter of 1995. Compared with desflurane, sevoflurane has the additional advantage of being nonirritating to the airway; inhalational induction of anesthesia with sevoflurane is achieved rapidly and easily. The instability of sevoflurane with CO2 absorbents and its in vivo biotransformation produce potentially toxic byproducts. These byproducts, including Compound A and fluoride, have been extensively studied, and although the possibility for iatrogenic sequelae from sevoflurane exists, the likelihood of long-term toxicity appears quite low. Phase IV studies are indicated to determine the safety of administering sevoflurane (1) to renally impaired patients and (2) to any patient with fresh gas flows less than 2 L/min. Sevoflurane is otherwise very well tolerated and appears to offer the advantage of rapid and smooth induction and emergence from general anesthesia." @default.
• W2158595873 created "2016-06-24" @default.
• W2158595873 creator A5020257221 @default.
• W2158595873 creator A5038510970 @default.
• W2158595873 date "1995-11-01" @default.
• W2158595873 modified "2023-10-06" @default.
• W2158595873 title "Inhalational anesthetics: Desflurane and sevoflurane" @default.
• W2158595873 cites W1963791575 @default.
• W2158595873 cites W1965164929 @default.
• W2158595873 cites W1965271045 @default.
• W2158595873 cites W1966018234 @default.
• W2158595873 cites W1967259640 @default.
• W2158595873 cites W1969071473 @default.
• W2158595873 cites W1969284646 @default.
• W2158595873 cites W1969349278 @default.
• W2158595873 cites W1969728196 @default.
• W2158595873 cites W1970252947 @default.
• W2158595873 cites W1970766207 @default.
• W2158595873 cites W1971511918 @default.
• W2158595873 cites W1972301398 @default.
• W2158595873 cites W1974167652 @default.
• W2158595873 cites W1979646284 @default.
• W2158595873 cites W1979791331 @default.
• W2158595873 cites W1981593087 @default.
• W2158595873 cites W1983023213 @default.
• W2158595873 cites W1983191801 @default.
• W2158595873 cites W1983379439 @default.
• W2158595873 cites W1984327249 @default.
• W2158595873 cites W1985664113 @default.
• W2158595873 cites W1986145394 @default.
• W2158595873 cites W1986149086 @default.
• W2158595873 cites W1986209759 @default.
• W2158595873 cites W1987180839 @default.
• W2158595873 cites W1988889875 @default.
• W2158595873 cites W1989533604 @default.
• W2158595873 cites W1991252130 @default.
• W2158595873 cites W1992552493 @default.
• W2158595873 cites W1994289213 @default.
• W2158595873 cites W1994680126 @default.
• W2158595873 cites W1994768174 @default.
• W2158595873 cites W1996999868 @default.
• W2158595873 cites W1998919114 @default.
• W2158595873 cites W1999022235 @default.
• W2158595873 cites W2001419018 @default.
• W2158595873 cites W2004029177 @default.
• W2158595873 cites W2004071339 @default.
• W2158595873 cites W2005221667 @default.
• W2158595873 cites W2007322953 @default.
• W2158595873 cites W2008890205 @default.
• W2158595873 cites W2010125545 @default.
• W2158595873 cites W2012877925 @default.
• W2158595873 cites W2012911423 @default.
• W2158595873 cites W2013729502 @default.
• W2158595873 cites W2014708055 @default.
• W2158595873 cites W2016367711 @default.
• W2158595873 cites W2016622860 @default.
• W2158595873 cites W2019043731 @default.
• W2158595873 cites W2019362706 @default.
• W2158595873 cites W2020334139 @default.
• W2158595873 cites W2021400180 @default.
• W2158595873 cites W2021528109 @default.
• W2158595873 cites W2021718664 @default.
• W2158595873 cites W2024360651 @default.
• W2158595873 cites W2026522943 @default.
• W2158595873 cites W2026895046 @default.
• W2158595873 cites W2027222124 @default.
• W2158595873 cites W2027610941 @default.
• W2158595873 cites W2028785168 @default.
• W2158595873 cites W2029977853 @default.
• W2158595873 cites W2030186867 @default.
• W2158595873 cites W2030707043 @default.
• W2158595873 cites W2030879141 @default.
• W2158595873 cites W2030904219 @default.
• W2158595873 cites W2032231709 @default.
• W2158595873 cites W2033687737 @default.
• W2158595873 cites W2034413765 @default.
• W2158595873 cites W2036292151 @default.
• W2158595873 cites W2038350778 @default.
• W2158595873 cites W2039256828 @default.
• W2158595873 cites W2039783701 @default.
• W2158595873 cites W2039803575 @default.
• W2158595873 cites W2040119026 @default.
• W2158595873 cites W2040818260 @default.
• W2158595873 cites W2042460548 @default.
• W2158595873 cites W2042611228 @default.
• W2158595873 cites W2042688337 @default.
• W2158595873 cites W2043509471 @default.
• W2158595873 cites W2047739127 @default.
• W2158595873 cites W2049587507 @default.
• W2158595873 cites W2050433147 @default.
• W2158595873 cites W2050927843 @default.
• W2158595873 cites W2051281037 @default.
• W2158595873 cites W2051413797 @default.
• W2158595873 cites W2051585402 @default.
• W2158595873 cites W2052457957 @default.
• W2158595873 cites W2056070717 @default.
• W2158595873 cites W2057223094 @default.
• W2158595873 cites W2057335473 @default.

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