Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158602227> ?p ?o ?g. }
- W2158602227 endingPage "472" @default.
- W2158602227 startingPage "468" @default.
- W2158602227 abstract "The naturally occurring flavonoids caused strand scission of DNA in the presence of copper ion. Flavonoids such as myricetin, baicalein, and quercetin as well as ascorbic acid cleaved plasmid pBR322 DNA and calf thymus DNA potently. Addition of catalase protected DNA from the strand breaks caused by flavonoids. Treatment of calf thymus DNA with these flavonoids or ascorbate plus copper produced 8-hydroxy-2′-deoxyguanosine. Cuprous ion reduced by flavonoids and ascorbic acid may play a key role in the oxidative cleavage of DNA and the formation of base adduct. Mutagenic and carcinogenic action of flavonoids may be explained by the prooxidant effects of the compounds." @default.
- W2158602227 created "2016-06-24" @default.
- W2158602227 creator A5002483949 @default.
- W2158602227 creator A5029591066 @default.
- W2158602227 creator A5049220245 @default.
- W2158602227 creator A5082034099 @default.
- W2158602227 date "1999-12-01" @default.
- W2158602227 modified "2023-10-17" @default.
- W2158602227 title "Prooxidant Activity of Flavonoids: Copper-Dependent Strand Breaks and the Formation of 8-Hydroxy-2′-Deoxyguanosine in DNA" @default.
- W2158602227 cites W1520543508 @default.
- W2158602227 cites W1590116013 @default.
- W2158602227 cites W1971748722 @default.
- W2158602227 cites W1988587391 @default.
- W2158602227 cites W2001628109 @default.
- W2158602227 cites W2023677185 @default.
- W2158602227 cites W2031809710 @default.
- W2158602227 cites W2034426588 @default.
- W2158602227 cites W2036174238 @default.
- W2158602227 cites W2045898150 @default.
- W2158602227 cites W2051075400 @default.
- W2158602227 cites W2054386186 @default.
- W2158602227 cites W2058000339 @default.
- W2158602227 cites W2059123383 @default.
- W2158602227 cites W2063059327 @default.
- W2158602227 cites W2069297991 @default.
- W2158602227 cites W2071636994 @default.
- W2158602227 cites W2086498426 @default.
- W2158602227 cites W2087177372 @default.
- W2158602227 cites W2140220133 @default.
- W2158602227 cites W2164931507 @default.
- W2158602227 cites W4232586362 @default.
- W2158602227 doi "https://doi.org/10.1006/mgme.1999.2901" @default.
- W2158602227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10607476" @default.
- W2158602227 hasPublicationYear "1999" @default.
- W2158602227 type Work @default.
- W2158602227 sameAs 2158602227 @default.
- W2158602227 citedByCount "94" @default.
- W2158602227 countsByYear W21586022272012 @default.
- W2158602227 countsByYear W21586022272014 @default.
- W2158602227 countsByYear W21586022272015 @default.
- W2158602227 countsByYear W21586022272016 @default.
- W2158602227 countsByYear W21586022272017 @default.
- W2158602227 countsByYear W21586022272018 @default.
- W2158602227 countsByYear W21586022272019 @default.
- W2158602227 countsByYear W21586022272020 @default.
- W2158602227 countsByYear W21586022272021 @default.
- W2158602227 countsByYear W21586022272022 @default.
- W2158602227 countsByYear W21586022272023 @default.
- W2158602227 crossrefType "journal-article" @default.
- W2158602227 hasAuthorship W2158602227A5002483949 @default.
- W2158602227 hasAuthorship W2158602227A5029591066 @default.
- W2158602227 hasAuthorship W2158602227A5049220245 @default.
- W2158602227 hasAuthorship W2158602227A5082034099 @default.
- W2158602227 hasConcept C143425029 @default.
- W2158602227 hasConcept C185592680 @default.
- W2158602227 hasConcept C2777810353 @default.
- W2158602227 hasConcept C2778004101 @default.
- W2158602227 hasConcept C2778173338 @default.
- W2158602227 hasConcept C2780441211 @default.
- W2158602227 hasConcept C2781263971 @default.
- W2158602227 hasConcept C2781466915 @default.
- W2158602227 hasConcept C2986274086 @default.
- W2158602227 hasConcept C31903555 @default.
- W2158602227 hasConcept C552990157 @default.
- W2158602227 hasConcept C55493867 @default.
- W2158602227 hasConcept C86803240 @default.
- W2158602227 hasConcept C98274493 @default.
- W2158602227 hasConceptScore W2158602227C143425029 @default.
- W2158602227 hasConceptScore W2158602227C185592680 @default.
- W2158602227 hasConceptScore W2158602227C2777810353 @default.
- W2158602227 hasConceptScore W2158602227C2778004101 @default.
- W2158602227 hasConceptScore W2158602227C2778173338 @default.
- W2158602227 hasConceptScore W2158602227C2780441211 @default.
- W2158602227 hasConceptScore W2158602227C2781263971 @default.
- W2158602227 hasConceptScore W2158602227C2781466915 @default.
- W2158602227 hasConceptScore W2158602227C2986274086 @default.
- W2158602227 hasConceptScore W2158602227C31903555 @default.
- W2158602227 hasConceptScore W2158602227C552990157 @default.
- W2158602227 hasConceptScore W2158602227C55493867 @default.
- W2158602227 hasConceptScore W2158602227C86803240 @default.
- W2158602227 hasConceptScore W2158602227C98274493 @default.
- W2158602227 hasFunder F4320320912 @default.
- W2158602227 hasIssue "4" @default.
- W2158602227 hasLocation W21586022271 @default.
- W2158602227 hasLocation W21586022272 @default.
- W2158602227 hasOpenAccess W2158602227 @default.
- W2158602227 hasPrimaryLocation W21586022271 @default.
- W2158602227 hasRelatedWork W1851468133 @default.
- W2158602227 hasRelatedWork W1973428220 @default.
- W2158602227 hasRelatedWork W1981412436 @default.
- W2158602227 hasRelatedWork W1986112503 @default.
- W2158602227 hasRelatedWork W2003790854 @default.
- W2158602227 hasRelatedWork W202580898 @default.
- W2158602227 hasRelatedWork W2158602227 @default.
- W2158602227 hasRelatedWork W2350973044 @default.
- W2158602227 hasRelatedWork W2990468985 @default.
- W2158602227 hasRelatedWork W2343233289 @default.
- W2158602227 hasVolume "68" @default.