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- W2158648119 abstract "Purpose: Tumor-associated angiogenesis and increased cellular proliferation in superficial transitional cell carcinoma (TCC) of the bladder represent promising new therapeutic targets, and have emerged as important prognostic indicators for cancer treatment. To our knowledge, these factors have not been studied in recurrent superficial TCC specimens treated with Bacillus Calmette-Guerin (BCG). The purpose of our study was to investigate the clinicopathologic response of BCG instillation on microvessel density (MVD) and cellular proliferation in recurrent superficial TCC of the bladder. Materials and methods: A total of 20 specimens from 10 patients were analyzed: 10 before (control group) and 10 after (treatment group) a 6 week instillation of BCG. In all specimens, tumor grade, MVD and cellular proliferation were analyzed in a blinded fashion. MVD was calculated by counting the number of blood vessels in the superficial lamina propria per high-power field. Immunohistochemistry was used to assess the expr..." @default.
- W2158648119 created "2016-06-24" @default.
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- W2158648119 date "2004-03-01" @default.
- W2158648119 modified "2023-09-26" @default.
- W2158648119 title "The Effect of BCG on Angiogenesis and Cellular Proliferation in Recurrent Superficial TCC of the Bladder" @default.
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- W2158648119 doi "https://doi.org/10.1080/1561095042000191664" @default.
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