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- W2158671864 endingPage "S757" @default.
- W2158671864 startingPage "S752" @default.
- W2158671864 abstract "Puerperal uterine infection, or endomyometritis, occurs more commonly after cesarean section than after vaginal birth. With the rate of cesarean delivery almost 25% of all births in this country, such infection is relatively common. The classic therapy for postcesarean endomyometritis is the combination of clindamycin and an aminoglycoside, usually gentamicin or tobramycin. This regimen has requisite antimicrobial activity against the aerobes and anaerobes of the cervicovaginal flora that usually cause this illness. In the last decade, however, the availability of broad-spectrum beta-lactam antibiotics has enabled the clinician to combat postcesarean infection with single-agent antimicrobial chemotherapy, or monotherapy. Higher-generation cephalosporins such as cefoxitin, cefotetan, and moxalactam, as well as the semisynthetic penicillins ticarcillin, piperacillin, and mezlocillin, have all been used alone in the therapy for postpartum infection. The addition of a beta-lactamase inhibitor to this class of drugs now offers a further resource to the practitioner if beta-lactamase-mediated antibiotic resistance arises in the patient population being treated." @default.
- W2158671864 created "2016-06-24" @default.
- W2158671864 creator A5000255160 @default.
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- W2158671864 date "1991-07-01" @default.
- W2158671864 modified "2023-10-16" @default.
- W2158671864 title "Antibiotic Therapy for Postcesarean Endomyometritis" @default.
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- W2158671864 doi "https://doi.org/10.1093/clinids/13.supplement_9.s752" @default.
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