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- W2158697067 abstract "Social interaction deficits and restricted repetitive behaviors and interests that characterize autism spectrum disorders (ASDs) may both reflect aberrant functioning of brain reward circuits. However, no neuroimaging study to date has investigated the integrity of reward circuits using an incentive delay paradigm in individuals with ASDs. In the present study, we used functional magnetic resonance imaging to assess blood-oxygen level-dependent activation during reward anticipation and outcomes in 15 participants with an ASD and 16 matched control participants. Brain activation was assessed during anticipation of and in response to monetary incentives and object image incentives previously shown to be visually salient for individuals with ASDs (e.g., trains, electronics). Participants with ASDs showed decreased nucleus accumbens activation during monetary anticipation and outcomes, but not during object anticipation or outcomes. Group × reward-type-interaction tests revealed robust interaction effects in bilateral nucleus accumbens during reward anticipation and in ventromedial prefrontal cortex during reward outcomes, indicating differential responses contingent on reward type in these regions. Results suggest that ASDs are characterized by reward-circuitry hypoactivation in response to monetary incentives but not in response to autism-relevant object images. The clinical implications of the double dissociation of reward type and temporal phase in reward circuitry function in ASD are discussed." @default.
- W2158697067 created "2016-06-24" @default.
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- W2158697067 date "2010-12-08" @default.
- W2158697067 modified "2023-09-26" @default.
- W2158697067 title "Reward circuitry function in autism spectrum disorders" @default.
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- W2158697067 cites W1963700723 @default.
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- W2158697067 cites W1967922673 @default.
- W2158697067 cites W1972778574 @default.
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- W2158697067 cites W1973745459 @default.
- W2158697067 cites W1975227851 @default.
- W2158697067 cites W1975417628 @default.
- W2158697067 cites W1978660262 @default.
- W2158697067 cites W1979595525 @default.
- W2158697067 cites W1981030752 @default.
- W2158697067 cites W2000400885 @default.
- W2158697067 cites W2002834809 @default.
- W2158697067 cites W2004300026 @default.
- W2158697067 cites W2006096283 @default.
- W2158697067 cites W2007382757 @default.
- W2158697067 cites W2010392115 @default.
- W2158697067 cites W2021702619 @default.
- W2158697067 cites W2022490111 @default.
- W2158697067 cites W2024365408 @default.
- W2158697067 cites W2028980996 @default.
- W2158697067 cites W2031238076 @default.
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- W2158697067 cites W2084331056 @default.
- W2158697067 cites W2085306492 @default.
- W2158697067 cites W2092083729 @default.
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- W2158697067 cites W2097833812 @default.
- W2158697067 cites W2098044398 @default.
- W2158697067 cites W2098766452 @default.
- W2158697067 cites W2099404168 @default.
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- W2158697067 cites W2138500196 @default.
- W2158697067 cites W2140078950 @default.
- W2158697067 cites W2144446993 @default.
- W2158697067 cites W2148726987 @default.
- W2158697067 cites W2154811018 @default.
- W2158697067 cites W2155944216 @default.
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- W2158697067 cites W2169427911 @default.
- W2158697067 cites W2170355135 @default.
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- W2158697067 doi "https://doi.org/10.1093/scan/nsq095" @default.
- W2158697067 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3277365" @default.
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- W2158697067 hasPublicationYear "2010" @default.
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