Matches in SemOpenAlex for { <https://semopenalex.org/work/W2158881352> ?p ?o ?g. }
- W2158881352 endingPage "734" @default.
- W2158881352 startingPage "730" @default.
- W2158881352 abstract "Human DNA polymerase ε is composed of a 261 kDa catalytic polypeptide and a 55 kDa small subunit of unknown function. cDNAs encoding the small subunit of human and mouse DNA polymerase ε were cloned. The predicted polypeptides have molecular masses of 59.469 and 59.319 kDa respectively and they are 90% identical. The human and mouse polypeptides show 22% identity with the 80 kDa subunit of the five subunit DNA polymerase ε from the yeast Saccharomyces cerevisiae. The high degree of conservation suggests that the 55 kDa subunit shares an essential function with the yeast 80 kDa subunit, which was earlier suggested to be involved in S phase cell cycle control in a pathway that is able to sense and signal incomplete replication. The small subunits of human and mouse DNA polymerase ε also show homology to the C-terminal domain of the second largest subunit of DNA polymerase α. The gene for the small subunit of human DNA polymerase ε (POLE2) was localized to chromosome 14q21–q22 by fluorescence in situ hybridization." @default.
- W2158881352 created "2016-06-24" @default.
- W2158881352 creator A5026714255 @default.
- W2158881352 creator A5026879682 @default.
- W2158881352 creator A5032534504 @default.
- W2158881352 creator A5052668307 @default.
- W2158881352 creator A5067204984 @default.
- W2158881352 creator A5069361080 @default.
- W2158881352 date "1998-02-01" @default.
- W2158881352 modified "2023-09-27" @default.
- W2158881352 title "The small subunits of human and mouse DNA polymerase epsilon are homologous to the second largest subunit of the yeast Saccharomyces cerevisiae DNA polymerase epsilon" @default.
- W2158881352 cites W1483340372 @default.
- W2158881352 cites W1507370496 @default.
- W2158881352 cites W1527517879 @default.
- W2158881352 cites W1529710337 @default.
- W2158881352 cites W1546570611 @default.
- W2158881352 cites W1547330783 @default.
- W2158881352 cites W1608564947 @default.
- W2158881352 cites W1637596780 @default.
- W2158881352 cites W1669999604 @default.
- W2158881352 cites W1824120105 @default.
- W2158881352 cites W1850062430 @default.
- W2158881352 cites W1861750438 @default.
- W2158881352 cites W1962559236 @default.
- W2158881352 cites W1971602039 @default.
- W2158881352 cites W1979915680 @default.
- W2158881352 cites W1980721353 @default.
- W2158881352 cites W2001586358 @default.
- W2158881352 cites W2006986579 @default.
- W2158881352 cites W2013648875 @default.
- W2158881352 cites W2017928245 @default.
- W2158881352 cites W2020982275 @default.
- W2158881352 cites W2029108786 @default.
- W2158881352 cites W2033551028 @default.
- W2158881352 cites W2033860372 @default.
- W2158881352 cites W2051582515 @default.
- W2158881352 cites W2055348937 @default.
- W2158881352 cites W2062713986 @default.
- W2158881352 cites W206882731 @default.
- W2158881352 cites W2079843180 @default.
- W2158881352 cites W2105743406 @default.
- W2158881352 cites W2136238750 @default.
- W2158881352 cites W2138270253 @default.
- W2158881352 cites W2144705335 @default.
- W2158881352 cites W2156211930 @default.
- W2158881352 doi "https://doi.org/10.1093/nar/26.3.730" @default.
- W2158881352 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/147316" @default.
- W2158881352 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9443964" @default.
- W2158881352 hasPublicationYear "1998" @default.
- W2158881352 type Work @default.
- W2158881352 sameAs 2158881352 @default.
- W2158881352 citedByCount "16" @default.
- W2158881352 crossrefType "journal-article" @default.
- W2158881352 hasAuthorship W2158881352A5026714255 @default.
- W2158881352 hasAuthorship W2158881352A5026879682 @default.
- W2158881352 hasAuthorship W2158881352A5032534504 @default.
- W2158881352 hasAuthorship W2158881352A5052668307 @default.
- W2158881352 hasAuthorship W2158881352A5067204984 @default.
- W2158881352 hasAuthorship W2158881352A5069361080 @default.
- W2158881352 hasBestOaLocation W21588813521 @default.
- W2158881352 hasConcept C103549609 @default.
- W2158881352 hasConcept C104292427 @default.
- W2158881352 hasConcept C104317684 @default.
- W2158881352 hasConcept C153911025 @default.
- W2158881352 hasConcept C156719811 @default.
- W2158881352 hasConcept C164965036 @default.
- W2158881352 hasConcept C2756471 @default.
- W2158881352 hasConcept C31254050 @default.
- W2158881352 hasConcept C41258723 @default.
- W2158881352 hasConcept C49105822 @default.
- W2158881352 hasConcept C552990157 @default.
- W2158881352 hasConcept C55493867 @default.
- W2158881352 hasConcept C73573662 @default.
- W2158881352 hasConcept C76535049 @default.
- W2158881352 hasConcept C82381507 @default.
- W2158881352 hasConcept C86803240 @default.
- W2158881352 hasConcept C88354546 @default.
- W2158881352 hasConceptScore W2158881352C103549609 @default.
- W2158881352 hasConceptScore W2158881352C104292427 @default.
- W2158881352 hasConceptScore W2158881352C104317684 @default.
- W2158881352 hasConceptScore W2158881352C153911025 @default.
- W2158881352 hasConceptScore W2158881352C156719811 @default.
- W2158881352 hasConceptScore W2158881352C164965036 @default.
- W2158881352 hasConceptScore W2158881352C2756471 @default.
- W2158881352 hasConceptScore W2158881352C31254050 @default.
- W2158881352 hasConceptScore W2158881352C41258723 @default.
- W2158881352 hasConceptScore W2158881352C49105822 @default.
- W2158881352 hasConceptScore W2158881352C552990157 @default.
- W2158881352 hasConceptScore W2158881352C55493867 @default.
- W2158881352 hasConceptScore W2158881352C73573662 @default.
- W2158881352 hasConceptScore W2158881352C76535049 @default.
- W2158881352 hasConceptScore W2158881352C82381507 @default.
- W2158881352 hasConceptScore W2158881352C86803240 @default.
- W2158881352 hasConceptScore W2158881352C88354546 @default.
- W2158881352 hasIssue "3" @default.
- W2158881352 hasLocation W21588813521 @default.
- W2158881352 hasLocation W21588813522 @default.
- W2158881352 hasLocation W21588813523 @default.