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• W2158920391 endingPage "2594" @default.
• W2158920391 startingPage "2587" @default.
• W2158920391 abstract "Summary The gene encoding the herpes simplex virus type 1 (HSV-1) glycoprotein C (gC) was isolated and cloned into a vaccinia virus insertion vector, and the resulting vaccinia-gC vector was used to construct a recombinant vaccinia virus that expressed gC (VVgC5). Infection of cells with VVgC5 resulted in cell surface expression of authentic HSV-1 gC. HSV-1 gC-specific neutralizing antibodies were produced in VVgC5-immunized mice, and lymphocytes exhibited an HSV-1-specific proliferation response in vitro following infection. More importantly, VVgC5-immunized mice were resistant to subsequent lethal HSV-1 challenge." @default.
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• W2158920391 date "1989-10-01" @default.
• W2158920391 modified "2023-10-16" @default.
• W2158920391 title "Recombinant Vaccinia Virus Expressing the Herpes Simplex Virus Type 1 Glycoprotein C Protects Mice against Herpes Simplex Virus Challenge" @default.
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• W2158920391 doi "https://doi.org/10.1099/0022-1317-70-10-2587" @default.
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