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- W2158983349 abstract "A pyrrolepolyamide-deoxyguanosine hybrid using the 3-aminopropyl linker (GAP) was designed and synthesized on the basis of previously reported results of a pyrrolepolyamide-adenosine hybrid (Apy) and a pyrrolepolyamide-deoxyguanoside hybrid using the 3-aminopropionyl linker (GBP). An evaluation of the DNA binding sequence selectivity of GAP was performed by analysis of CD spectra and Tm values using three DNA duplexes. It was shown that GAP possessed greater binding specificity than distamycin A, netropsin, Apy and GBP." @default.
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- W2158983349 date "2004-11-01" @default.
- W2158983349 modified "2023-09-23" @default.
- W2158983349 title "Design, synthesis and analysis of a pyrrolepolyamide-nucleoside hybrid" @default.
- W2158983349 doi "https://doi.org/10.1093/nass/48.1.55" @default.
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